Exercise and respiratory tract viral infections

Stephen A. Martin, Brandt D. Pence, Jeffrey A. Woods

Research output: Contribution to journalReview article

Abstract

Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.

Original languageEnglish (US)
Pages (from-to)157-164
Number of pages8
JournalExercise and Sport Sciences Reviews
Volume37
Issue number4
DOIs
StatePublished - Oct 1 2009

Fingerprint

Virus Diseases
Respiratory Tract Infections
Immunosuppression
Hormones
Inflammation
Phenotype

Keywords

  • Inflammation
  • Influenza
  • Physical activity
  • URTI
  • Virus

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Exercise and respiratory tract viral infections. / Martin, Stephen A.; Pence, Brandt D.; Woods, Jeffrey A.

In: Exercise and Sport Sciences Reviews, Vol. 37, No. 4, 01.10.2009, p. 157-164.

Research output: Contribution to journalReview article

Martin, Stephen A. ; Pence, Brandt D. ; Woods, Jeffrey A. / Exercise and respiratory tract viral infections. In: Exercise and Sport Sciences Reviews. 2009 ; Vol. 37, No. 4. pp. 157-164.
@article{be27cf5dcd4e49c5bed98431b0c2d7a4,
title = "Exercise and respiratory tract viral infections",
abstract = "Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.",
keywords = "Inflammation, Influenza, Physical activity, URTI, Virus",
author = "Martin, {Stephen A.} and Pence, {Brandt D.} and Woods, {Jeffrey A.}",
year = "2009",
month = "10",
day = "1",
doi = "10.1097/JES.0b013e3181b7b57b",
language = "English (US)",
volume = "37",
pages = "157--164",
journal = "Exercise and Sport Sciences Reviews",
issn = "0091-6331",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Exercise and respiratory tract viral infections

AU - Martin, Stephen A.

AU - Pence, Brandt D.

AU - Woods, Jeffrey A.

PY - 2009/10/1

Y1 - 2009/10/1

N2 - Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.

AB - Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.

KW - Inflammation

KW - Influenza

KW - Physical activity

KW - URTI

KW - Virus

UR - http://www.scopus.com/inward/record.url?scp=70349661464&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70349661464&partnerID=8YFLogxK

U2 - 10.1097/JES.0b013e3181b7b57b

DO - 10.1097/JES.0b013e3181b7b57b

M3 - Review article

C2 - 19955864

AN - SCOPUS:70349661464

VL - 37

SP - 157

EP - 164

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

SN - 0091-6331

IS - 4

ER -