Abstract
Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 157-164 |
| Number of pages | 8 |
| Journal | Exercise and Sport Sciences Reviews |
| Volume | 37 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 1 2009 |
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Keywords
- Inflammation
- Influenza
- Physical activity
- URTI
- Virus
ASJC Scopus subject areas
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Exercise and respiratory tract viral infections. / Martin, Stephen A.; Pence, Brandt D.; Woods, Jeffrey A.
In: Exercise and Sport Sciences Reviews, Vol. 37, No. 4, 01.10.2009, p. 157-164.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Exercise and respiratory tract viral infections
AU - Martin, Stephen A.
AU - Pence, Brandt D.
AU - Woods, Jeffrey A.
PY - 2009/10/1
Y1 - 2009/10/1
N2 - Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.
AB - Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.
KW - Inflammation
KW - Influenza
KW - Physical activity
KW - URTI
KW - Virus
UR - http://www.scopus.com/inward/record.url?scp=70349661464&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349661464&partnerID=8YFLogxK
U2 - 10.1097/JES.0b013e3181b7b57b
DO - 10.1097/JES.0b013e3181b7b57b
M3 - Review article
C2 - 19955864
AN - SCOPUS:70349661464
VL - 37
SP - 157
EP - 164
JO - Exercise and Sport Sciences Reviews
JF - Exercise and Sport Sciences Reviews
SN - 0091-6331
IS - 4
ER -