The effects of exercise on mature cells of the hematopoietic lineage have been well characterized; however, the effects of exercise on the more primitive cells of the hematopoietic system are unknown. Here, we propose that the benefits of exercise apply to hematopoietic progenitors and that exercise increases hematopoietic stem cell quantity primarily mediated via adaptations in the stem cell niche.
- bone marrow transplantation
- exercise training
- hematopoietic stem cell
ASJC Scopus subject areas
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation