Exact distance measurements for structure and dynamics in solid proteins by fast-magic-angle-spinning NMR

Kristof Grohe, Evgeny Nimerovsky, Himanshu Singh, Suresh K. Vasa, Benedikt Söldner, Beat Vögeli, Chad M. Rienstra, Rasmus Linser

Research output: Contribution to journalArticle

Abstract

Fast-magic-angle-spinning solid-state NMR is a developing technique for determination of protein structure and dynamics. Proton-proton correlations usually lead to rough distance restraints, a serious hurdle towards high-resolution structures. Analogous to the "eNOE" concept in solution, an integrative approach for more accurate restraints enables improved structural accuracy with minimal analytical effort.

Original languageEnglish (US)
Pages (from-to)7899-7902
Number of pages4
JournalChemical Communications
Volume55
Issue number55
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Grohe, K., Nimerovsky, E., Singh, H., Vasa, S. K., Söldner, B., Vögeli, B., Rienstra, C. M., & Linser, R. (2019). Exact distance measurements for structure and dynamics in solid proteins by fast-magic-angle-spinning NMR. Chemical Communications, 55(55), 7899-7902. https://doi.org/10.1039/c9cc02317h