TY - JOUR
T1 - Evolution of the diverse antifreeze proteins
AU - Cheng, Chi Hing C.
PY - 1998/12
Y1 - 1998/12
N2 - Different types of ice-growth-inhibiting antifreeze proteins, first recognized in fish, have now been isolated from insects and plants, and the list continues to expand. Their structures are amazingly diverse; how they attain the same function are subjects of intense research. Evolutionary precursors of several members have been identified - divergent proteins of apparently unrelated function. The hybridization of information from structural and molecular evolution studies of these molecules provides a forum in which issues of selection, gene genealogy, adaptive evolution, and invention of a novel function can be coherently addressed.
AB - Different types of ice-growth-inhibiting antifreeze proteins, first recognized in fish, have now been isolated from insects and plants, and the list continues to expand. Their structures are amazingly diverse; how they attain the same function are subjects of intense research. Evolutionary precursors of several members have been identified - divergent proteins of apparently unrelated function. The hybridization of information from structural and molecular evolution studies of these molecules provides a forum in which issues of selection, gene genealogy, adaptive evolution, and invention of a novel function can be coherently addressed.
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U2 - 10.1016/S0959-437X(98)80042-7
DO - 10.1016/S0959-437X(98)80042-7
M3 - Article
C2 - 9914209
AN - SCOPUS:0031771585
SN - 0959-437X
VL - 8
SP - 715
EP - 720
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
IS - 6
ER -