Evidence for the ISG15-specific deubiquitinase usp18 as an antineoplastic target

Keyphrases

• Antineoplastic Target 100%
• Apoptosis 12%
• Cancer Cell Growth 12%
• Cancer Formation 12%
• Cancer Growth 12%
• Conjugated Protein 12%
• Deubiquitinase 100%
• Genetic Loss 12%
• Growth Regulators 12%
• IFN-stimulated Genes 100%
• ISGylation 12%
• Lung Cancer Model 12%
• Murine Lung 12%
• Oncogenesis 12%
• Oncology 12%
• Oncoprotein 12%
• Pharmacologic Targets 12%
• Post-translational Modification 12%
• Regulatory Proteins 12%
• Substrate Proteins 12%
• Translational Relevance 12%
• Tumor Suppressor 12%
• Ubiquitin 12%
• Ubiquitin-like 25%
• Ubiquitin-specific Protease 18 100%
• Ubiquitination 12%
• USP18 100%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 9%
• Cancer Model 9%
• Carcinogenesis 9%
• Cell Growth 9%
• Conjugated Protein 9%
• Crystal Structure 9%
• Genetics 9%
• Posttranslational Modification 9%
• Programmed Cell Death 9%
• Protease 72%
• Tumor Suppressor Protein 9%
• Ubiquitin 100%
• Ubiquitination 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Cancer Growth 16%
• Cancer Model 8%
• Carcinogenesis 8%
• Deubiquitinase 100%
• Lung Cancer 8%
• Malignant Neoplasm 8%
• Oncoprotein 8%
• Regulator Protein 8%
• Tumor Suppressor Protein 8%
• Ubiquitin 25%