TY - JOUR
T1 - Evidence for impaired mnemonic strategy use among patients with schizophrenia using the part-list cuing paradigm
AU - Christensen, Bruce K.
AU - Girard, Todd A.
AU - Benjamin, Aaron S.
AU - Vidailhet, Pierre
N1 - Funding Information:
The authors are grateful to Stephanie Kerwin, Jennifer Bryan, Pushpinder Saini, and Krystle Martin for their assistance with stimuli preparation, participant recruitment/testing, and data management. Portions of this research were presented at the biennial meeting of the International Congress on Schizophrenia Research, Savannah, GA, 2005. This research was supported, in part, with a grant received from the Canadian Psychiatric Research Foundation.
Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2006/7
Y1 - 2006/7
N2 - Purpose: Strategic and mnemonic abilities of person with schizophrenia (SCZ) were studied using a part-list cuing (PLC) task. In this task, presentation of retrieval cues in the form of a subset of studied words typically impairs recall of the remaining items. This impairment is thought to reflect a disruption of participants' natural retrieval strategies. Methods: Participants with SCZ and healthy controls (ns = 28) studied word lists with three different levels of semantic organization: (a) unrelated, (b) categorized, but presented in a random order, and (c) presented by category. For each type of list, participants recalled words under both free-recall and PLC conditions. Results: Consistent with SCZ-related impairment of strategic retrieval processes, the SCZ group was less disrupted by PLC interference than controls in the unrelated-list condition. Comparison of free recall across lists also indicated a consistent deficit in SCZ despite varying levels of difficulty and retrieval contexts. Nonetheless, the SCZ group demonstrated parallel improvement to the healthy group with increasing list organization. Conclusions: These results provide evidence of deficient retrieval processes in SCZ in a context placing maximal requirements for utilization of self-initiated, effortful, mnemonic strategies. Unlike most extant results demonstrating mnemonic impairment in persons with SCZ, the present results cannot be accounted for by task difficulty; SCZ participants' recall was less disrupted by PLC than was that of healthy participants. Results also demonstrated that SCZ participants could benefit, in terms of recall and strategy use, from list organization when this structure was explicitly provided at test.
AB - Purpose: Strategic and mnemonic abilities of person with schizophrenia (SCZ) were studied using a part-list cuing (PLC) task. In this task, presentation of retrieval cues in the form of a subset of studied words typically impairs recall of the remaining items. This impairment is thought to reflect a disruption of participants' natural retrieval strategies. Methods: Participants with SCZ and healthy controls (ns = 28) studied word lists with three different levels of semantic organization: (a) unrelated, (b) categorized, but presented in a random order, and (c) presented by category. For each type of list, participants recalled words under both free-recall and PLC conditions. Results: Consistent with SCZ-related impairment of strategic retrieval processes, the SCZ group was less disrupted by PLC interference than controls in the unrelated-list condition. Comparison of free recall across lists also indicated a consistent deficit in SCZ despite varying levels of difficulty and retrieval contexts. Nonetheless, the SCZ group demonstrated parallel improvement to the healthy group with increasing list organization. Conclusions: These results provide evidence of deficient retrieval processes in SCZ in a context placing maximal requirements for utilization of self-initiated, effortful, mnemonic strategies. Unlike most extant results demonstrating mnemonic impairment in persons with SCZ, the present results cannot be accounted for by task difficulty; SCZ participants' recall was less disrupted by PLC than was that of healthy participants. Results also demonstrated that SCZ participants could benefit, in terms of recall and strategy use, from list organization when this structure was explicitly provided at test.
KW - Memory
KW - Mnemonic strategy
KW - Part-list cuing interference
KW - Schizophrenia
KW - Semantic organization
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U2 - 10.1016/j.schres.2006.03.001
DO - 10.1016/j.schres.2006.03.001
M3 - Article
C2 - 16632330
AN - SCOPUS:33745356615
SN - 0920-9964
VL - 85
SP - 1
EP - 11
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -