TY - JOUR
T1 - Evaluation of two point-of-care meters and a portable chemistry analyzer for measurement of blood glucose concentrations in juvenile white-tailed deer (Odocoileus virginianus)
AU - Burdick, Stacy
AU - Mitchell, Mark A.
AU - Neil, Johanna
AU - Heggem, Brittany
AU - Whittington, Julia
AU - Acierno, Mark J.
PY - 2012/3/1
Y1 - 2012/3/1
N2 - Objective-To evaluate agreement of blood glucose concentrations measured in juvenile white-tailed deer (Odocoileus virginianus) by use of 2 point-of-care (POC) blood glucose meters and 1 portable chemistry analyzer with values obtained in serum by use of a standard laboratory chemistry analyzer, and to evaluate agreement between results obtained with the 2 POC meters. Design-Prospective evaluation study. Sample-14 venous blood samples from 14 healthy white-tailed deer fawns. Procedures-Blood glucose concentration was measured with each of 2 POC meters. The remainder of the sample was divided into 2 tubes (1 that contained lithium heparin and 1 with no anticoagulant). Glucose concentration in anticoagulated whole blood was measured with the portable analyzer. Serum was collected from the remaining sample for measurement of glucose concentrations with the laboratory analyzer. Bland-Altman plots were used to assess agreement. Results-Agreement between POC blood glucose meters and the laboratory analyzer was poor; mean values for bias were 2.9 mg/dL (95% limits of agreement [LOA], -70.2 to 76.0 mg/dL) and -30.8 mg/dL (95% LOA, -111.6 to 49.9 mg/dL), respectively. Agreement between the 2 POC meters was also poor (bias, 31.0 mg/dL; 95% LOA, -47.2 to 109.2 mg/dL). Agreement between the portable analyzer and the laboratory analyzer was good (bias, -1.6 mg/dL; 95% LOA, -15.3 to 12.1 mg/dL). Conclusions and Clinical Relevance-Results suggested that the POC blood glucose meters used in this study are not appropriate for measurement of blood glucose concentrations in juvenile white-tailed deer.
AB - Objective-To evaluate agreement of blood glucose concentrations measured in juvenile white-tailed deer (Odocoileus virginianus) by use of 2 point-of-care (POC) blood glucose meters and 1 portable chemistry analyzer with values obtained in serum by use of a standard laboratory chemistry analyzer, and to evaluate agreement between results obtained with the 2 POC meters. Design-Prospective evaluation study. Sample-14 venous blood samples from 14 healthy white-tailed deer fawns. Procedures-Blood glucose concentration was measured with each of 2 POC meters. The remainder of the sample was divided into 2 tubes (1 that contained lithium heparin and 1 with no anticoagulant). Glucose concentration in anticoagulated whole blood was measured with the portable analyzer. Serum was collected from the remaining sample for measurement of glucose concentrations with the laboratory analyzer. Bland-Altman plots were used to assess agreement. Results-Agreement between POC blood glucose meters and the laboratory analyzer was poor; mean values for bias were 2.9 mg/dL (95% limits of agreement [LOA], -70.2 to 76.0 mg/dL) and -30.8 mg/dL (95% LOA, -111.6 to 49.9 mg/dL), respectively. Agreement between the 2 POC meters was also poor (bias, 31.0 mg/dL; 95% LOA, -47.2 to 109.2 mg/dL). Agreement between the portable analyzer and the laboratory analyzer was good (bias, -1.6 mg/dL; 95% LOA, -15.3 to 12.1 mg/dL). Conclusions and Clinical Relevance-Results suggested that the POC blood glucose meters used in this study are not appropriate for measurement of blood glucose concentrations in juvenile white-tailed deer.
UR - http://www.scopus.com/inward/record.url?scp=84857434861&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84857434861&partnerID=8YFLogxK
U2 - 10.2460/javma.240.5.596
DO - 10.2460/javma.240.5.596
M3 - Article
C2 - 22332630
AN - SCOPUS:84857434861
VL - 240
SP - 596
EP - 599
JO - Journal of the American Veterinary Medical Association
JF - Journal of the American Veterinary Medical Association
SN - 0003-1488
IS - 5
ER -