Evaluation of Topical Epidural Analgesia Delivered in Gelfoam for Postoperative Hemilaminectomy Pain Control

Jessica R. Barker, Stuart C. Clark-Price, Wanda J. Gordon-Evans

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate efficacy of a topical epidural analgesia used alone, or in combination with hydromorphone, against a standard pain protocol for the 48 hours immediately after hemilaminectomy. Study Design: Randomized, blinded, controlled, clinical trial. Animals: Dogs (n = 30) with thoracolumbar intervertebral disc disease treated with hemilaminectomy. Methods: Dogs were randomly divided into 3 groups: group 1 received intermittent hydromorphone postoperatively, group 2 received a topical epidural of preservative-free morphine and dexmedetomidine administered via gel foam, group 3 received both forms of analgesia. All dogs were monitored and assessed for pain for 48 hours immediately postoperatively. Data were analyzed using MANOVA and Wilcoxon Rank Sum Tests. Results: There was a significant temporal difference in treatment groups 1 and 3 when using a 0-10 pain scale (MANOVA, P = .02). There was also a significant difference at the 48th hour postoperatively between groups 1 and 3 (Wilcoxon Rank Sum Test). Conclusion: Topical epidural of preservative-free morphine and dexmedetomidine administered via gelfoam is not sufficient analgesia alone post hemilaminectomy but in conjunction with other opioid administration may lead to superior pain relief.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalVeterinary Surgery
Volume42
Issue number1
DOIs
StatePublished - Jan 2013

ASJC Scopus subject areas

  • veterinary(all)

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