Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model

Sarah M. Gray; Santiago D. Gutierrez-Nibeyro; Laurent L. Couëtil; Gavin P. Horn; Richard M. Kesler; Annette M. McCoy; Matt C. Stewart; David J. Schaeffer

doi:10.1111/vsu.13690

Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model

Sarah M. Gray, Santiago D. Gutierrez-Nibeyro, Laurent L. Couëtil, Gavin P. Horn, Richard M. Kesler, Annette M. McCoy, Matt C. Stewart, David J. Schaeffer

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To evaluate the airway mechanics of modified toggle LP constructs in an airflow chamber model and compare these to the airway mechanics of standard LP constructs. Study design: Ex-vivo experimental study. Sample population: Fifty-one equine cadaveric larynges. Methods: Bilateral LP constructs were performed using a modified toggle (n = 23) or a standard (n = 21) LP technique. Constructs were tested in an airflow model before and after cyclic loading which was designed to mimic postoperative swallowing. The cross-sectional area (CSA), peak translaryngeal airflow (L/s), and impedance (cmH₂0/L/s) were determined and compared between LP constructs before and after cycling. Results: The mean CSA of the rima glottidis of the modified toggle LP constructs was 15.2 ± 2.6 cm² before and 14.7 ± 2.6 cm² after cyclic loading, and the mean CSA of the rima glottidis of the standard LP constructs was 16.4 ± 2.9 cm² before and 15.7 ± 2.8 cm² after cyclic loading. The modified toggle LP constructs had similar peak translaryngeal impedance before and after cyclic loading (p =.13); however, the standard LP constructs had higher peak translaryngeal impedance after cyclic loading (p =.02). Conclusion: The modified toggle and standard LP constructs had comparable airway mechanics in an ex-vivo model. Clinical significance: Further investigation is warranted to determine the extent to which the modified toggle LP technique restores normal airway function in horses with RLN.

Original language	English (US)
Pages (from-to)	1409-1417
Number of pages	9
Journal	Veterinary Surgery
Volume	50
Issue number	7
DOIs	https://doi.org/10.1111/vsu.13690
State	Published - Oct 2021

ASJC Scopus subject areas

General Veterinary

Online availability

10.1111/vsu.13690

Library availability

Discover UIUC Full Text

Cite this

@article{7c33b01d57a14a939b5438455cb4832b,

title = "Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model",

abstract = "Objective: To evaluate the airway mechanics of modified toggle LP constructs in an airflow chamber model and compare these to the airway mechanics of standard LP constructs. Study design: Ex-vivo experimental study. Sample population: Fifty-one equine cadaveric larynges. Methods: Bilateral LP constructs were performed using a modified toggle (n = 23) or a standard (n = 21) LP technique. Constructs were tested in an airflow model before and after cyclic loading which was designed to mimic postoperative swallowing. The cross-sectional area (CSA), peak translaryngeal airflow (L/s), and impedance (cmH20/L/s) were determined and compared between LP constructs before and after cycling. Results: The mean CSA of the rima glottidis of the modified toggle LP constructs was 15.2 ± 2.6 cm2 before and 14.7 ± 2.6 cm2 after cyclic loading, and the mean CSA of the rima glottidis of the standard LP constructs was 16.4 ± 2.9 cm2 before and 15.7 ± 2.8 cm2 after cyclic loading. The modified toggle LP constructs had similar peak translaryngeal impedance before and after cyclic loading (p =.13); however, the standard LP constructs had higher peak translaryngeal impedance after cyclic loading (p =.02). Conclusion: The modified toggle and standard LP constructs had comparable airway mechanics in an ex-vivo model. Clinical significance: Further investigation is warranted to determine the extent to which the modified toggle LP technique restores normal airway function in horses with RLN.",

author = "Gray, {Sarah M.} and Gutierrez-Nibeyro, {Santiago D.} and Cou{\"e}til, {Laurent L.} and Horn, {Gavin P.} and Kesler, {Richard M.} and McCoy, {Annette M.} and Stewart, {Matt C.} and Schaeffer, {David J.}",

note = "Funding Information: This manuscript represents a portion of a thesis to be submitted by Dr. Gray to the University of Illinois (Department of Clinical Veterinary Medicine) as partial fulfillment of the requirements for a Master of Science degree. The authors would like to express their gratitude to Dr. Norm Durcharme and Mr. Leo Soderholm for their guidance in building the flow-chamber. We also would like to express our gratitude to Dr. Kara Lascola for assisting with the initial data collection in the preliminary portion of the study. Animal use: Specimens used for the study were obtained from client owned horses humanely euthanized due to severe or terminal diseases associated with systems other than the respiratory tract. The specimens for the study were used if there was owner's consent. Funding Information: This work is funded by the Cooperative State Research Service, U.S. Department of Agriculture (Project No: ILLU‐888‐347) and Arthrex. Publisher Copyright: {\textcopyright} 2021 American College of Veterinary Surgeons.",

year = "2021",

month = oct,

doi = "10.1111/vsu.13690",

language = "English (US)",

volume = "50",

pages = "1409--1417",

journal = "Veterinary Surgery",

issn = "0161-3499",

publisher = "Wiley-Blackwell",

number = "7",

}

TY - JOUR

T1 - Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model

AU - Gray, Sarah M.

AU - Gutierrez-Nibeyro, Santiago D.

AU - Couëtil, Laurent L.

AU - Horn, Gavin P.

AU - Kesler, Richard M.

AU - McCoy, Annette M.

AU - Stewart, Matt C.

AU - Schaeffer, David J.

N1 - Funding Information: This manuscript represents a portion of a thesis to be submitted by Dr. Gray to the University of Illinois (Department of Clinical Veterinary Medicine) as partial fulfillment of the requirements for a Master of Science degree. The authors would like to express their gratitude to Dr. Norm Durcharme and Mr. Leo Soderholm for their guidance in building the flow-chamber. We also would like to express our gratitude to Dr. Kara Lascola for assisting with the initial data collection in the preliminary portion of the study. Animal use: Specimens used for the study were obtained from client owned horses humanely euthanized due to severe or terminal diseases associated with systems other than the respiratory tract. The specimens for the study were used if there was owner's consent. Funding Information: This work is funded by the Cooperative State Research Service, U.S. Department of Agriculture (Project No: ILLU‐888‐347) and Arthrex. Publisher Copyright: © 2021 American College of Veterinary Surgeons.

PY - 2021/10

Y1 - 2021/10

N2 - Objective: To evaluate the airway mechanics of modified toggle LP constructs in an airflow chamber model and compare these to the airway mechanics of standard LP constructs. Study design: Ex-vivo experimental study. Sample population: Fifty-one equine cadaveric larynges. Methods: Bilateral LP constructs were performed using a modified toggle (n = 23) or a standard (n = 21) LP technique. Constructs were tested in an airflow model before and after cyclic loading which was designed to mimic postoperative swallowing. The cross-sectional area (CSA), peak translaryngeal airflow (L/s), and impedance (cmH20/L/s) were determined and compared between LP constructs before and after cycling. Results: The mean CSA of the rima glottidis of the modified toggle LP constructs was 15.2 ± 2.6 cm2 before and 14.7 ± 2.6 cm2 after cyclic loading, and the mean CSA of the rima glottidis of the standard LP constructs was 16.4 ± 2.9 cm2 before and 15.7 ± 2.8 cm2 after cyclic loading. The modified toggle LP constructs had similar peak translaryngeal impedance before and after cyclic loading (p =.13); however, the standard LP constructs had higher peak translaryngeal impedance after cyclic loading (p =.02). Conclusion: The modified toggle and standard LP constructs had comparable airway mechanics in an ex-vivo model. Clinical significance: Further investigation is warranted to determine the extent to which the modified toggle LP technique restores normal airway function in horses with RLN.

AB - Objective: To evaluate the airway mechanics of modified toggle LP constructs in an airflow chamber model and compare these to the airway mechanics of standard LP constructs. Study design: Ex-vivo experimental study. Sample population: Fifty-one equine cadaveric larynges. Methods: Bilateral LP constructs were performed using a modified toggle (n = 23) or a standard (n = 21) LP technique. Constructs were tested in an airflow model before and after cyclic loading which was designed to mimic postoperative swallowing. The cross-sectional area (CSA), peak translaryngeal airflow (L/s), and impedance (cmH20/L/s) were determined and compared between LP constructs before and after cycling. Results: The mean CSA of the rima glottidis of the modified toggle LP constructs was 15.2 ± 2.6 cm2 before and 14.7 ± 2.6 cm2 after cyclic loading, and the mean CSA of the rima glottidis of the standard LP constructs was 16.4 ± 2.9 cm2 before and 15.7 ± 2.8 cm2 after cyclic loading. The modified toggle LP constructs had similar peak translaryngeal impedance before and after cyclic loading (p =.13); however, the standard LP constructs had higher peak translaryngeal impedance after cyclic loading (p =.02). Conclusion: The modified toggle and standard LP constructs had comparable airway mechanics in an ex-vivo model. Clinical significance: Further investigation is warranted to determine the extent to which the modified toggle LP technique restores normal airway function in horses with RLN.

UR - http://www.scopus.com/inward/record.url?scp=85111615788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85111615788&partnerID=8YFLogxK

U2 - 10.1111/vsu.13690

DO - 10.1111/vsu.13690

M3 - Article

C2 - 34309058

AN - SCOPUS:85111615788

SN - 0161-3499

VL - 50

SP - 1409

EP - 1417

JO - Veterinary Surgery

JF - Veterinary Surgery

IS - 7

ER -

Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model

Abstract

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this