Evaluation of chitosan/biphasic calcium phosphate scaffolds for maxillofacial bone tissue engineering

Aylin Sendemir Urkmez; Sherrie G. Clark; Matthew B. Wheeler; Michael S. Goldwasser; Russell D. Jamison

doi:10.1002/masy.200850912

Evaluation of chitosan/biphasic calcium phosphate scaffolds for maxillofacial bone tissue engineering

Aylin Sendemir Urkmez, Sherrie G. Clark, Matthew B. Wheeler, Michael S. Goldwasser, Russell D. Jamison

Research output: Contribution to journal › Article › peer-review

Abstract

Porous, 30 chitosan/biphasic calcium phosphate (BCP) scaffolds were used to prepare tissue engineering constructs for maxillofacial bone tissue reconstruction. Mesenchymal stem cells (MSC's) were seeded and cultured on clinically relevant sized scaffolds. In vitro engineered constructs facilitated the healing of mandibular defects in pigs if accompanied with delivery of basic fibroblast growth factor (bFGF).

Original language	English (US)
Pages (from-to)	100-105
Number of pages	6
Journal	Macromolecular Symposia
Volume	269
Issue number	1
DOIs	https://doi.org/10.1002/masy.200850912
State	Published - Aug 2008

Keywords

Biomaterials
Biphasic calcium phosphate (BCP)
Bone tissue engineering
Chitosan
Scaffold

ASJC Scopus subject areas

Organic Chemistry
Materials Chemistry
Polymers and Plastics
Condensed Matter Physics

Online availability

10.1002/masy.200850912

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abstract = "Porous, 30 chitosan/biphasic calcium phosphate (BCP) scaffolds were used to prepare tissue engineering constructs for maxillofacial bone tissue reconstruction. Mesenchymal stem cells (MSC's) were seeded and cultured on clinically relevant sized scaffolds. In vitro engineered constructs facilitated the healing of mandibular defects in pigs if accompanied with delivery of basic fibroblast growth factor (bFGF).",

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AU - Jamison, Russell D.

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AB - Porous, 30 chitosan/biphasic calcium phosphate (BCP) scaffolds were used to prepare tissue engineering constructs for maxillofacial bone tissue reconstruction. Mesenchymal stem cells (MSC's) were seeded and cultured on clinically relevant sized scaffolds. In vitro engineered constructs facilitated the healing of mandibular defects in pigs if accompanied with delivery of basic fibroblast growth factor (bFGF).

KW - Biomaterials

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Evaluation of chitosan/biphasic calcium phosphate scaffolds for maxillofacial bone tissue engineering

Abstract

Keywords

ASJC Scopus subject areas

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