@article{a1802ddc3b0f45d2a8ba2e73af3dcb5f,
title = "Ethynyl MIDA boronate: A readily accessible and highly versatile building block for small molecule synthesis",
abstract = "Ethynyl N-methyliminodiacetic acid (MIDA) boronate is a very useful building block for small molecule synthesis. This compound can serve as both a bifunctional acetylene equivalent with the capacity for terminus-selective bis-functionalization and a versatile starting material for the preparation of a wide range of other MIDA boronate building blocks.",
keywords = "Alkynes Sonogashira coupling, Diels-Alder, Iterative cross-coupling, MIDA boronates, Small molecule synthesis",
author = "Struble, {Justin R.} and Lee, {Suk Joong} and Burke, {Martin D.}",
note = "Funding Information: We gratefully acknowledge E.M. Woerly and E.P. Gillis for performing the synthesis of 7 and 8 , respectively. We also thank the NSF (CAREER 0747778 ), Howard Hughes Medical Institute , the Arnold and Mabel Beckman Foundation , and Bristol-Myers Squibb for financial support, Dr. Danielle Gray and Amy Fuller for X-ray crystallographic analysis, and Dr. Steve Mullen and Furong Sun for mass spectral analysis. M.D.B. is a Howard Hughes Medical Institute Early Career Scientist, Beckman Young Investigator, Sloan Foundation Research Fellow, Dreyfus New Faculty Awardee, Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry Awardee, Eli Lilly Grantee, Amgen Young Investigator, and AstraZeneca Excellence in Chemistry Awardee. ",
year = "2010",
month = jun,
day = "26",
doi = "10.1016/j.tet.2010.04.020",
language = "English (US)",
volume = "66",
pages = "4710--4718",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Ltd",
number = "26",
}