Estrogen Receptor-Based Imaging Agents. 1. Synthesis and Receptor Binding Affinity of Some Aromatic and D-Ring Halogenated Estrogens

Keyphrases

• Estrogen Receptor 100%
• Estrogen 100%
• Imaging Agents 100%
• Aromatic Ring 100%
• Halogenated 100%
• Receptor Binding Affinity 100%
• Receptor-based 100%
• D-ring 100%
• Ortho 80%
• Estradiol 80%
• Binding Affinity 60%
• Bromo 40%
• 17-estradiol 40%
• Human Breast Tumor 40%
• Halogenation 40%
• Halogens 40%
• Monosubstituted 40%
• Steroid Estrogens 40%
• Phenolic Hydroxyl Group 40%
• Aromatics 20%
• Methyl Ester 20%
• Epimerization 20%
• Acetate 20%
• Disubstituted 20%
• Radioisotopes 20%
• High Specific Activity 20%
• Epimer 20%
• Fluorinated 20%
• Receptor Affinity 20%
• 2-substituted 20%
• A-ring 20%
• Estrone 20%
• Competitive Binding Assay 20%
• Hydride Reduction 20%
• Nonsteroidal Estrogens 20%
• Enol Acetates 20%
• Fluoro Compounds 20%
• Estrone Derivatives 20%

Chemistry

• Receptor Binding Affinity 100%
• Diethylstilbestrol 100%
• Kd 50%
• Phenol 33%
• Halogen 33%
• halogenation 33%
• Estrone 33%
• Methyl Ester 16%
• Radioisotope 16%
• Fluorine 16%
• Epimer 16%
• Enol 16%
• Non Steroidal Estrogen 16%
• Schiemann Fluorination 16%
• Epimerization 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Receptor 100%
• Diethylstilbestrol 100%
• Estrogen Receptor 100%
• Breast Tumor 33%
• Phenol 33%
• Radioisotope 16%
• Estrone 16%
• Estrogens 16%
• Estrone Derivative 16%