Laminated safety glass samples with different levels of adhesive bond strength were manufactured and tested using mechanical guided waves. The adhesive bond strength of the test samples was then also evaluated using the commonly used destructive testing method, i.e., the pummel test method. The imperfect interfaces between the plastic interface and the two adjacent glass plates were modeled using a bed of longitudinal and shear springs. The spring constants were estimated using fracture mechanics concepts in conjunction with surface analysis of the plastic interlayer and of the two adjacent glass plates using atomic force microscopy and profilometer measurements. In addition to mode shape analysis, the phase and energy velocities were calculated and discussed. The guided wave theoretical predictions of adhesion levels (obtained using this multilayered model) were validated using the pummel test results. Results show that this approach is useful in the nondestructive assessment of adhesive bond strength in laminated safety glass.