Equine viral arteritis in newborn foals: Clinical, pathological, serological, microbiological and immunohistochemical observations

F. Del Piero, Pamela A. Wilkins, J. W. Lopez, Amy L. Glaser, E. J. Dubovi, D. H. Schlafer, D. H. Lein

Research output: Contribution to journalArticle

Abstract

Clinical, pathological, immunohistochemical, serological and microbiological findings are described for 2 geographically and temporally distinct equine arteritis virus (EAV) epidemics in newborn foals. Outbreak A occurred at a commercial Standardbred breeding facility; Outbreak B began in a group of research animals. Clinical signs were severe and primarily referrable to the respiratory tract. Fever and leucopenia and/or thrombocytopenia were observed in foals surviving for more than 24 h. The most common gross pathological findings were limited to the respiratory tract. Common histopathological findings included interstitial pneumonia, lymphocytic arteritis and periarteritis with fibrinoid necrosis of the tunica media. Renal tubular necrosis was noted in 2 foals. Immunoperoxidase histochemistry combined with virus isolation was diagnostic in all cases.

Original languageEnglish (US)
Pages (from-to)178-185
Number of pages8
JournalEquine veterinary journal
Volume29
Issue number3
DOIs
StatePublished - 1997
Externally publishedYes

Keywords

  • Epidemic
  • Equine arteritis virus
  • Foal
  • Horse

ASJC Scopus subject areas

  • Equine

Fingerprint Dive into the research topics of 'Equine viral arteritis in newborn foals: Clinical, pathological, serological, microbiological and immunohistochemical observations'. Together they form a unique fingerprint.

  • Cite this