Equine keratomycosis

Paula Diniz Galera, Bianca da Costa Martins, José Luiz Laus, Dennis Brooks

Research output: Contribution to journalReview articlepeer-review


Environmental and behavioral factors make horses susceptible to corneal and conjunctival lesions, since these structures are constantly exposed to bacteria and fungi specially Aspergillus spp. and Fusarium spp. Bacterial and fungal ulcerative keratitis, as well as non-ulcerative fungal keratitis such as stromal abscess, are frequent in horses. A "cascade" effect follows the initial lesion which triggers the release of inflammatory cytokines followed by an acute and severe infiltrate of polymorphonuclear cells in the cornea. The cornea becomes susceptible to the activity of proteolytic enzymes released by microorganisms and polymorphonuclear cells, resulting in stromal degradation and ocular perforation. The medical treatment targeting the corneal disease and the controlling of reflexive uveitis should be aggressive and surgical therapy should be associated in most of the cases. This paper reviews the pathophysiology of keratomycosis in horses and specific aspects of the treatment in this species.

Original languageEnglish (US)
Pages (from-to)1223-1230
Number of pages8
JournalCiencia Rural
Issue number7
StatePublished - Jul 2012
Externally publishedYes


  • Equine
  • Fungal
  • Keratomycosis
  • Stromal abscess
  • Ulcerative keratitis

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Agronomy and Crop Science
  • General Veterinary


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