Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members

Keyphrases

• Methylation 100%
• DNA Methylation (DNAm) 100%
• Dynamic Molecular 100%
• Family Members 100%
• Molecular Adaptation 100%
• DNMT3A 100%
• Genetic Modulators 100%
• Epigenetic Engineering 100%
• DNA Methyltransferase 1 (DNMT1) 66%
• Adaptation 33%
• Human Disease 33%
• Network Level 33%
• Hypo 33%
• Stress Response 33%
• Simulated Annealing 33%
• Knock-in Mouse Model 33%
• Epigenetics 33%
• Hypermethylation 33%
• Poly(A) 33%
• Dynamic Networks 33%
• Essential Metabolite 33%
• Time-course Expression 33%
• 5-hydroxymethylcytosine (5hmC) 33%
• Evolutionarily Conserved 33%
• Overlap Function 33%
• Hypomethylation 33%
• Genomic Features 33%
• S-adenosylmethionine 33%
• CpG Methylation 33%
• Gene Methylation 33%
• Partially Overlapped 33%
• Human DNA 33%
• Methylation Pattern 33%
• Interpretation Method 33%
• Sequence Preference 33%
• Convolutional Neural Network 33%
• Yeast Species 33%
• Spatial Units 33%
• Methylation Data 33%
• DNA Methyltransferase Genes 33%
• Komagataella Phaffii 33%
• Endogenous DNA 33%
• Nucleosome Repeat Length 33%
• Epigenetic Perturbation 33%
• Methylated Cytosine 33%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Methylation 100%
• Epigenetics 100%
• DNA Methylation 50%
• DNA Methyltransferase 50%
• Nucleosome 33%
• Genomics 33%
• Cytosine 33%
• Metabolite 16%
• Transcription 16%
• S-Adenosyl Methionine 16%
• Komagataella 16%