Epi-illumination diffraction phase microscopy with white light

C. Edwards, B. Bhaduri, B. G. Griffin, L. L. Goddard, G. Popescu

Research output: Contribution to journalArticle

Abstract

We demonstrate the first reflection-based epi-illumination diffraction phase microscope with white light (epi-wDPM). The epi-wDPM system combines the off-axis, common-path, and white light approaches, in a reflection geometry enabling sub-nanometer spatial and temporal noise levels, while providing single-shot acquisition for opaque samples. We verified the epi-wDPM results by measuring control samples with known dimensions and comparing them to measurements from other well-established techniques. We imaged gold-coated HeLa cells to illustrate the tradeoffs between epi-wDPM with low and high spatial coherence.

Original languageEnglish (US)
Pages (from-to)6162-6165
Number of pages4
JournalOptics Letters
Volume39
Issue number21
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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