Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Thao M. Xiong; Edzna S. Garcia; Junfeng Chen; Lingyang Zhu; Ariale J. Alzona; Steven C. Zimmerman

doi:10.1039/d1cc05578j

Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Thao M. Xiong, Edzna S. Garcia, Junfeng Chen, Lingyang Zhu, Ariale J. Alzona, Steven C. Zimmerman

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst "cofactors"and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.

Original language	English (US)
Pages (from-to)	985-988
Number of pages	4
Journal	Chemical Communications
Volume	58
Issue number	7
DOIs	https://doi.org/10.1039/d1cc05578j
State	Published - Jan 21 2022

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/d1cc05578j

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AU - Alzona, Ariale J.

AU - Zimmerman, Steven C.

PY - 2022/1/21

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Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Abstract

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