Abstract
The drastically increasing amount of plastic waste is causing an environmental crisis that requires innovative technologies for recycling post-consumer plastics to achieve waste valorization while meeting environmental quality goals. Biocatalytic depolymerization mediated by enzymes has emerged as an efficient and sustainable alternative for plastic treatment and recycling. A variety of plastic-degrading enzymes have been discovered from microbial sources. Meanwhile, protein engineering has been exploited to modify and optimize plastic-degrading enzymes. This review highlights the recent trends and up-to-date advances in mining novel plastic-degrading enzymes through state-of-the-art omics-based techniques and improving the enzyme catalytic efficiency and stability via various protein engineering strategies. Future research prospects and challenges are also discussed.
Original language | English (US) |
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Pages (from-to) | 22-37 |
Number of pages | 16 |
Journal | Trends in Biotechnology |
Volume | 40 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2022 |
Externally published | Yes |
Keywords
- biocatalysis
- omics-based techniques
- plastic depolymerization
- plastic-degrading enzymes
- protein engineering
- sustainable plastic recycling
ASJC Scopus subject areas
- Biotechnology
- Bioengineering