Environmental factors in infertility

Kathleen S. Hruska, Priscilla A. Furth, David B. Seifer, Fady I. Sharara, Jodi A. Flaws

Research output: Contribution to journalReview article

Abstract

In conclusion, several studies indicate that there is an association between cigarette smoking and adverse reproductive outcomes in women as well as men. Some studies indicate that alcohol consumption impairs the reproductive capacity of women. Exposures to PCE in the dry cleaning industry, toluene in the printing business, ethylene oxide and mixed solvents have been associated with decreased fecundity. Abnormalities in sperm production have been found in men exposed to radiant heat or heavy metals. Environmental exposure to chlorinated hydrocarbons (eg, DDT, PCB, pentachlorophenol, hexachlorocyclohexane) has been associated with an increase in rates of miscarriage and endometriosis. Clinicians should counsel patients who are trying to achieve a successful pregnancy to stop smoking and limit alcohol intake. Clinicians can additionally counsel patients who are in contact with potentially harmful occupational and environmental toxicants to limit their exposure. It is important to recognize, however, that many of the studies to date are limited by small sample size, poor exposure assessment, poor outcome measurements, recruitment bias, or recall bias. Additional studies will be necessary to clarify the magnitude of risk associated with these factors.

Original languageEnglish (US)
Pages (from-to)821-829
Number of pages9
JournalClinical Obstetrics and Gynecology
Volume43
Issue number4
DOIs
StatePublished - Dec 1 2000
Externally publishedYes

Fingerprint

Infertility
Smoking
Pentachlorophenol
Chlorinated Hydrocarbons
Lindane
Ethylene Oxide
Printing
DDT
Polychlorinated Biphenyls
Environmental Exposure
Toluene
Spontaneous Abortion
Endometriosis
Heavy Metals
Alcohol Drinking
Sample Size
Fertility
Spermatozoa
Industry
Hot Temperature

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Environmental factors in infertility. / Hruska, Kathleen S.; Furth, Priscilla A.; Seifer, David B.; Sharara, Fady I.; Flaws, Jodi A.

In: Clinical Obstetrics and Gynecology, Vol. 43, No. 4, 01.12.2000, p. 821-829.

Research output: Contribution to journalReview article

Hruska, KS, Furth, PA, Seifer, DB, Sharara, FI & Flaws, JA 2000, 'Environmental factors in infertility', Clinical Obstetrics and Gynecology, vol. 43, no. 4, pp. 821-829. https://doi.org/10.1097/00003081-200012000-00014
Hruska, Kathleen S. ; Furth, Priscilla A. ; Seifer, David B. ; Sharara, Fady I. ; Flaws, Jodi A. / Environmental factors in infertility. In: Clinical Obstetrics and Gynecology. 2000 ; Vol. 43, No. 4. pp. 821-829.
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