Enhanced amperometric detection of glucose using Si 29 particles

Gang Wang, Kevin Mantey, Munir H. Nayfeh, Siu Tung Yau

Research output: Contribution to journalArticlepeer-review


The 1 nm Si29 particle is used as the sensing element for an enzyme-free amperometric electrochemical glucose sensor. The sensor shows selective glucose detection against interfering substances at physiological concentrations with long-term stability, reusability, and the absence of electrode poisoning. The Si29 particle is significantly more efficient in generating signal current compared to both dissolved and immobilized enzyme. This observation suggests that the particle can be used to replace enzyme in making glucose sensors and that the particle is a suitable material for the realization of nanoscale devices that generate signals sufficiently high for use.

Original languageEnglish (US)
Article number243901
JournalApplied Physics Letters
Issue number24
StatePublished - 2006

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)


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