We have developed a facile and simple method to synthesize magnetic microspheres and delivery of them into living cells. Visualization of endocytosis was done via optical and electron microscopy. Magnetic microspheres were produced using an ultrasonic spray pyrolysis (USP) technique and were analyzed using XRD, SEM, (S)TEM, and SQUID. Cellular experiments were conducted using two mammalian cell lines. Key in the visualization process is the use of PDMS (poly(dimethylsiloxane) as the substrate of cell growth.
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