Enantioselective Synthesis of γ-Lactams by Lewis Base Catalyzed Sulfenoamidation of Alkenes

Keyphrases

• Base Hydrolysis 100%
• Alkenes 100%
• Lewis Bases 100%
• Lactams 100%
• Enantioselective Synthesis 100%
• Amides 50%
• Sulfur 50%
• Electrophile 50%
• Enantioselectivity 50%
• Cyclization 50%
• Thioether 50%
• Sulfonyl 50%
• Sulfonamides 50%
• Enantioenriched 50%
• Lewis Base Catalyst 50%
• Thiiranium Ions 50%
• Lewis Base Activation 50%
• Carboxamide 50%
• Electron-deficient Alkenes 50%

Chemistry

• Alkene 100%
• Lewis Base 100%
• Lactam 100%
• Carboxamide 66%
• Electrophile 33%
• Sulfide 33%
• Base Catalyst 33%
• Sulfonamide 33%