Enantioselective ring opening of epoxides with silicon tetrachloride in the presence of a chiral lewis base: Mechanism studies

Keyphrases

• (R)-1 33%
• Asymmetric Amplification 33%
• Base Mechanism 100%
• Chiral Base 100%
• Chiral Phosphoramidites 33%
• Chloride 33%
• Chlorohydrins 33%
• Enantiomerically Enriched 33%
• Enantioselectivity 100%
• Epoxide Ring Opening 100%
• Excellent Yields 33%
• Kinetic Study 33%
• Mechanism Study 100%
• Meso-epoxides 33%
• Olefins 33%
• Origin of Enantioselectivity 33%
• Ring Opening 33%
• SiCl4 100%
• Silicon Tetrachloride 100%
• Stereochemistry 33%
• Stoichiometry 33%
• Transition Structure 33%

Chemistry

• Acyclic Olefin 50%
• Cyclic Olefin 50%
• Enantioselectivity 50%
• Epoxide 100%
• Kinetic Study 50%
• Lewis Base 100%
• Phosphoramide 50%
• Reaction Stoichiometry 50%
• Ring Opening Reaction 100%
• Silicon 100%
• Stereochemistry 50%