Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging

Tomasz P. Wrobel; Matthew R. Kole; Rohit Bhargava

Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging

Tomasz P. Wrobel, Matthew R. Kole, Rohit Bhargava

Research output: Contribution to journal › Review article › peer-review

Abstract

Recent advances in instrumentation have enabled new forms of vibrational chemical imaging, including discrete-frequency infrared (DFIR) microscopy and stimulated Raman scattering (SRS) microscopy. These technologies may represent a fundamental shift in how we approach spectroscopic imaging: Rather than collecting full spectra that contain redundant information, measuring a few important spectral frequencies may enable significant gains in speed, throughput, signal-to-noise ratio, and image quality. For IR microscopy, these advantages may be compounded by high-definition IR microscopy. Here we discuss recent advances in IR and nonlinear Raman imaging through the lens of "discrete-frequency" approaches and include several examples of applications and critical issues in instrumentation that are likely to be dominant research themes in the near future.

Original language	English (US)
Journal	Spectroscopy (Santa Monica)
Volume	31
Issue number	6
State	Published - Jun 2016

ASJC Scopus subject areas

Analytical Chemistry
Atomic and Molecular Physics, and Optics
Spectroscopy

Library availability

Discover UIUC Full Text

Cite this

@article{70fc285608ae4fb8990ac648bd6462a8,

title = "Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging",

abstract = "Recent advances in instrumentation have enabled new forms of vibrational chemical imaging, including discrete-frequency infrared (DFIR) microscopy and stimulated Raman scattering (SRS) microscopy. These technologies may represent a fundamental shift in how we approach spectroscopic imaging: Rather than collecting full spectra that contain redundant information, measuring a few important spectral frequencies may enable significant gains in speed, throughput, signal-to-noise ratio, and image quality. For IR microscopy, these advantages may be compounded by high-definition IR microscopy. Here we discuss recent advances in IR and nonlinear Raman imaging through the lens of {"}discrete-frequency{"} approaches and include several examples of applications and critical issues in instrumentation that are likely to be dominant research themes in the near future.",

author = "Wrobel, {Tomasz P.} and Kole, {Matthew R.} and Rohit Bhargava",

note = "Funding Information: We would like to acknowledge generous support from the entities for resources that contributed toward or were featured in this review. We are grateful to Thermo Scientific for use of a Thermo Scientific DXR xi imaging microscope. We are thankful to Agilent Technology for equipment support. Thanks to the Martha Gillete Lab at the University of Illinois at Urbana-Champaign for the rat brain specimen. TPW acknowledges support through the {"}Mobility Plus{"} program from the Polish Ministry of Science and Higher Education. We gratefully acknowledge funding from the National Institutes of Health via grants R01EB009745, R21CA190120, and U01MH109062.",

year = "2016",

month = jun,

language = "English (US)",

volume = "31",

journal = "Spectroscopy (Santa Monica)",

issn = "0887-6703",

publisher = "Advanstar Communications",

number = "6",

}

TY - JOUR

T1 - Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging

AU - Wrobel, Tomasz P.

AU - Kole, Matthew R.

AU - Bhargava, Rohit

N1 - Funding Information: We would like to acknowledge generous support from the entities for resources that contributed toward or were featured in this review. We are grateful to Thermo Scientific for use of a Thermo Scientific DXR xi imaging microscope. We are thankful to Agilent Technology for equipment support. Thanks to the Martha Gillete Lab at the University of Illinois at Urbana-Champaign for the rat brain specimen. TPW acknowledges support through the "Mobility Plus" program from the Polish Ministry of Science and Higher Education. We gratefully acknowledge funding from the National Institutes of Health via grants R01EB009745, R21CA190120, and U01MH109062.

PY - 2016/6

Y1 - 2016/6

N2 - Recent advances in instrumentation have enabled new forms of vibrational chemical imaging, including discrete-frequency infrared (DFIR) microscopy and stimulated Raman scattering (SRS) microscopy. These technologies may represent a fundamental shift in how we approach spectroscopic imaging: Rather than collecting full spectra that contain redundant information, measuring a few important spectral frequencies may enable significant gains in speed, throughput, signal-to-noise ratio, and image quality. For IR microscopy, these advantages may be compounded by high-definition IR microscopy. Here we discuss recent advances in IR and nonlinear Raman imaging through the lens of "discrete-frequency" approaches and include several examples of applications and critical issues in instrumentation that are likely to be dominant research themes in the near future.

AB - Recent advances in instrumentation have enabled new forms of vibrational chemical imaging, including discrete-frequency infrared (DFIR) microscopy and stimulated Raman scattering (SRS) microscopy. These technologies may represent a fundamental shift in how we approach spectroscopic imaging: Rather than collecting full spectra that contain redundant information, measuring a few important spectral frequencies may enable significant gains in speed, throughput, signal-to-noise ratio, and image quality. For IR microscopy, these advantages may be compounded by high-definition IR microscopy. Here we discuss recent advances in IR and nonlinear Raman imaging through the lens of "discrete-frequency" approaches and include several examples of applications and critical issues in instrumentation that are likely to be dominant research themes in the near future.

UR - http://www.scopus.com/inward/record.url?scp=84974827236&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84974827236&partnerID=8YFLogxK

M3 - Review article

AN - SCOPUS:84974827236

SN - 0887-6703

VL - 31

JO - Spectroscopy (Santa Monica)

JF - Spectroscopy (Santa Monica)

IS - 6

ER -

Emerging trends and opportunities in discrete-frequency infrared and Raman spectroscopic imaging

Abstract

ASJC Scopus subject areas

Library availability

Related links

Fingerprint

Cite this