Recent advances in instrumentation have enabled new forms of vibrational chemical imaging, including discrete-frequency infrared (DFIR) microscopy and stimulated Raman scattering (SRS) microscopy. These technologies may represent a fundamental shift in how we approach spectroscopic imaging: Rather than collecting full spectra that contain redundant information, measuring a few important spectral frequencies may enable significant gains in speed, throughput, signal-to-noise ratio, and image quality. For IR microscopy, these advantages may be compounded by high-definition IR microscopy. Here we discuss recent advances in IR and nonlinear Raman imaging through the lens of "discrete-frequency" approaches and include several examples of applications and critical issues in instrumentation that are likely to be dominant research themes in the near future.
|Original language||English (US)|
|Journal||Spectroscopy (Santa Monica)|
|State||Published - Jun 2016|
ASJC Scopus subject areas
- Analytical Chemistry
- Atomic and Molecular Physics, and Optics