Electroretinography in the western gray kangaroo (Macropus fuliginosus)

Amber L. Labelle, Ralph E. Hamor, Kristina Narfström, Carrie B. Breaux

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To perform electroretinography on normal anesthetized western gray kangaroos (Macropus fuliginosus). Animals studied: Six captive western gray kangaroos. Procedures: The kangaroos were anesthetized using a combination of ketamine and medetomidine via a remote drug delivery system, then were maintained on isoflurane after endotracheal intubation and reversal of the medetomidine with atipamazole. After a minimum of 20 min of dark adaptation, electroretinograms were obtained using a handheld electroretinography (ERG) machine using a single flash protocol at three light intensities: 10 mcd.s/m2, 3000 mcd.s/m2, 10 000 mcd.s/m2. Results: At 10 mcd.s/m2 the mean b-wave amplitude and implicit time was 102.0 μV (SD ± 41.3 and 95% CI 68.9-135.1) and 78.4 ms (SD ± 8.3 and 95% CI 71.8-85.0). At 3000 mcd.s/m2 the mean a-wave amplitude and implicit time was 69.9 μV (SD ± 20.5 and 95% CI 53.5-86.3) and 17.6 ms (SD ± 1.5 and 95% CI 16.4-18.8) and the mean b-wave amplitude and implicit time was 175.4 μV (SD ± 35.9 and 95% CI 146.7-204.1) and 74.1 ms (SD ± 3.5 and 95% CI 71.2-76.9). At 10 000 mcd.s/m2 the mean a-wave amplitude and implicit time was 89.1 μV (SD ± 27.1 and 95% CI 67.5-110.8) and 16.8 ms (SD ± 1.0 and 95% CI 16.0-17.0) and the mean b-wave amplitude and implicit time was 203.7 μV (SD ± 41.4 and 95% CI 170.6-236.8) and 75.4 ms (SD ± 3.3 and 95% CI 72.8-78.1). Conclusion: Electroretinography outside of the typical clinical setting is feasible using a portable ERG system and allows for quick analysis of retinal function in exotic species.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalVeterinary Ophthalmology
Volume13
Issue numberSUPPL. 1
DOIs
StatePublished - Sep 2010

Keywords

  • Electroretinogram
  • Eye
  • Macropod
  • Macropus fuliginosus
  • Retina
  • Western gray kangaroo

ASJC Scopus subject areas

  • veterinary(all)

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