Electrochemically controlled Deconjugation and delivery of single quantum dots into the nucleus of living cells

Kyungsuk Yum, Ning Wang, Min Feng Yu

Research output: Contribution to journalArticlepeer-review

Abstract

A membrane-penetrating nanoneedle (also serving as a nanoelectrode) is developed for carrying and rapidly releasing individual quantum dots into the nucleus of a living cell via an electrochemical reaction activated by an electrical pulse. Direct delivery of biological probes into the nucleus with high spatial and temporal precision offers new strategies for the study of biological activity in a living cell.

Original languageEnglish (US)
Pages (from-to)2109-2113
Number of pages5
JournalSmall
Volume6
Issue number19
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • General Chemistry
  • Engineering (miscellaneous)
  • Biotechnology
  • General Materials Science
  • Biomaterials

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