Abstract
We use the theory of elasticity to compute the shape of the DNA loop bridging the gap in the crystal structure of the lac repressor-DNA complex. The Kirchhoff system of equations with boundary conditions derived from the crystal structure is solved using a continuation method. This approach can be applied effectively to find coarse-grained conformational minima of DNA loops.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4900-4903 |
| Number of pages | 4 |
| Journal | Physical review letters |
| Volume | 83 |
| Issue number | 23 |
| DOIs | |
| State | Published - Jan 1 1999 |
ASJC Scopus subject areas
- General Physics and Astronomy