Efficient dipolar double quantum filtering under magic angle spinning without a 1H decoupling field

Joseph M. Courtney, Chad M. Rienstra

Research output: Contribution to journalArticlepeer-review

Abstract

We present a systematic study of dipolar double quantum (DQ) filtering in 13C-labeled organic solids over a range of magic-angle spinning rates, using the SPC-n recoupling sequence element with a range of n symmetry values from 3 to 11. We find that efficient recoupling can be achieved for values n ≥ 7, provided that the 13C nutation frequency is on the order of 100 kHz or greater. The decoupling-field dependence was investigated and explicit heteronuclear decoupling interference conditions identified. The major determinant of DQ filtering efficiency is the decoupling interference between 13C and 1H fields. For 13C nutation frequencies greater than 75 kHz, optimal performance is observed without an applied 1H field. At spinning rates exceeding 20 kHz, symmetry conditions as low as n = 3 were found to perform adequately.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalJournal of Magnetic Resonance
Volume269
DOIs
StatePublished - Aug 1 2016

Keywords

  • Dipolar recoupling
  • Double quantum filtering
  • Fast magic-angle spinning
  • Heteronuclear decoupling
  • Proteins

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics

Fingerprint

Dive into the research topics of 'Efficient dipolar double quantum filtering under magic angle spinning without a <sup>1</sup>H decoupling field'. Together they form a unique fingerprint.

Cite this