Efficient and stereoselective cross-coupling with highly substituted alkenylsilanols

Scott E. Denmark; Weitao Pan

doi:10.1016/S0022-328X(02)01268-8

Efficient and stereoselective cross-coupling with highly substituted alkenylsilanols

Scott E. Denmark, Weitao Pan

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Highly substituted alkenylsilanols (1), readily prepared from commercially available simple starting materials, are efficiently coupled with aryl or alkenyl halides in the presence of tetrabutylammonium fluoride (TBAF) and a palladium(0) catalyst. Yields are generally high and the reactions are highly stereoselective and compatible with a wide range of functional groups.

Original language	English (US)
Pages (from-to)	98-104
Number of pages	7
Journal	Journal of Organometallic Chemistry
Volume	653
Issue number	1-2
DOIs	https://doi.org/10.1016/S0022-328X(02)01268-8
State	Published - Jul 1 2002

Keywords

Alkenylsilanols
Cross-coupling
Palladium catalysis

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
Materials Chemistry

Online availability

10.1016/S0022-328X(02)01268-8

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abstract = "Highly substituted alkenylsilanols (1), readily prepared from commercially available simple starting materials, are efficiently coupled with aryl or alkenyl halides in the presence of tetrabutylammonium fluoride (TBAF) and a palladium(0) catalyst. Yields are generally high and the reactions are highly stereoselective and compatible with a wide range of functional groups.",

keywords = "Alkenylsilanols, Cross-coupling, Palladium catalysis",

author = "Denmark, {Scott E.} and Weitao Pan",

note = "Funding Information: We are grateful to the National Science Foundation (NSF CHE9803124) for generous financial support. ",

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AU - Denmark, Scott E.

AU - Pan, Weitao

N1 - Funding Information: We are grateful to the National Science Foundation (NSF CHE9803124) for generous financial support.

PY - 2002/7/1

Y1 - 2002/7/1

N2 - Highly substituted alkenylsilanols (1), readily prepared from commercially available simple starting materials, are efficiently coupled with aryl or alkenyl halides in the presence of tetrabutylammonium fluoride (TBAF) and a palladium(0) catalyst. Yields are generally high and the reactions are highly stereoselective and compatible with a wide range of functional groups.

AB - Highly substituted alkenylsilanols (1), readily prepared from commercially available simple starting materials, are efficiently coupled with aryl or alkenyl halides in the presence of tetrabutylammonium fluoride (TBAF) and a palladium(0) catalyst. Yields are generally high and the reactions are highly stereoselective and compatible with a wide range of functional groups.

KW - Alkenylsilanols

KW - Cross-coupling

KW - Palladium catalysis

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JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 1-2

ER -

Efficient and stereoselective cross-coupling with highly substituted alkenylsilanols

Abstract

Keywords

ASJC Scopus subject areas

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