Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

T. L. Grubb, G. J. Benson, J. C. Thurmon, W. O. Olson, W. J. Tranquilli, Jonathan H Foreman, Peter D Constable, L. E. Davis

Research output: Contribution to journalArticlepeer-review

Abstract

Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.

Original languageEnglish (US)
Pages (from-to)6-11
Number of pages6
JournalVeterinary Anaesthesia and Analgesia
Volume24
Issue number2
DOIs
StatePublished - Dec 1997

ASJC Scopus subject areas

  • veterinary(all)

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