Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

T. L. Grubb; G. J. Benson; J. C. Thurmon; W. O. Olson; W. J. Tranquilli; J. H. Foreman; P. D. Constable; L. E. Davis

doi:10.1111/j.1467-2995.1997.tb00148.x

Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

T. L. Grubb, G. J. Benson, J. C. Thurmon, W. O. Olson, W. J. Tranquilli, J. H. Foreman, P. D. Constable, L. E. Davis

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Abstract

Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.

Original language	English (US)
Pages (from-to)	6-11
Number of pages	6
Journal	Veterinary Anaesthesia and Analgesia
Volume	24
Issue number	2
DOIs	https://doi.org/10.1111/j.1467-2995.1997.tb00148.x
State	Published - Dec 1997

ASJC Scopus subject areas

General Veterinary

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10.1111/j.1467-2995.1997.tb00148.x

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title = "Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses",

abstract = "Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.",

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year = "1997",

month = dec,

doi = "10.1111/j.1467-2995.1997.tb00148.x",

language = "English (US)",

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T1 - Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

AU - Grubb, T. L.

AU - Benson, G. J.

AU - Thurmon, J. C.

AU - Olson, W. O.

AU - Tranquilli, W. J.

AU - Foreman, J. H.

AU - Constable, P. D.

AU - Davis, L. E.

PY - 1997/12

Y1 - 1997/12

N2 - Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.

AB - Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.

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Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

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