Effects of thyroid hormones on serum and cutaneous fatty acid concentrations in dogs

K. L. Campbell, C. A. Davis

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of thyroid hormones on the serum and cutaneous fatty acid concentration profiles of dogs were evaluated. Thyroidectomized dogs had significant (P < 0.05) increases in serum oleic acid and linoleic acid concentrations, and decreases in concentration of dihomo-γ-linolenic acid, arachidonic acid, and other elongation products of fatty acid metabolism. These changes were reversed in response to thyroid hormone replacement. Similar changes were found in cutaneous fatty acid concentration profiles. Thus, in dogs, thyroid hormones may be involved in the regulation of fatty acid Δ-6-desaturase activity.

Original languageEnglish (US)
Pages (from-to)752-756
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume51
Issue number5
StatePublished - Sep 5 1990

ASJC Scopus subject areas

  • veterinary(all)

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