Effects of temperature, amebic strain, and carbohydrates on Acanthamoeba adherence to corneal epithelium in vitro

L. D. Morton, G. L. McLaughlin, H. E. Whiteley

Research output: Contribution to journalArticlepeer-review

Abstract

An in vitro coincubation assay was used to measure adhesion of radiolabeled Acanthamoeba trophozoites to corneal epithelium. Adhesion of amebae to corneal epithelium was higher at 25°C than at 37 or 4°C, did not consistently correlate with the reported pathogenicity of the strain of Acanthamoeba, and was inhibited by mannose and by methyl-α-D-mannopyranoside.

Original languageEnglish (US)
Pages (from-to)3819-3822
Number of pages4
JournalInfection and immunity
Volume59
Issue number10
StatePublished - 1991

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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