Effects of reallocating sedentary time with physical activity on quality of life indicators in breast cancer survivors

Whitney A. Welch, Diane Ehlers, Kara L. Gavin, Susan Aguinaga, Alison Cottrell, Anne Nielsen, Payton Solk, Edward McAuley, Siobhan M. Phillips

Research output: Contribution to journalArticle

Abstract

Objectives: Physical activity is associated with better quality of life (QOL) among breast cancer survivors. However, it is unknown the extent to which time spent sedentary or replacing this time with active behaviors may affect QOL. Our aim was to determine the effect of substituting time between sedentary and active behaviors on QOL indicators in breast cancer survivors. Methods: An isotemporal substitution approach was used to examine the associations of reallocating time to sedentary and active behaviors measured by accelerometry with Functional Assessment of Cancer Treatment—Breast (FACT-B; total, physical, social, emotional, functional well-being, and breast cancer–specific concerns) and the Hospital Anxiety and Depression Scale (HADS) scores in a pooled analysis of breast cancer survivors (n = 753; Mage = 56.9 ± 9.5 y) from two observational studies. Results: Reallocating 30 minutes of sedentary time to 30 minutes of moderate-to-vigorous intensity physical activity (MVPA) was associated with improved FACT-B total (B = 3.0; 95% CI, 0.6-4.5), physical well-being (B = 0.8; 95% CI, 0.33-1.2), and functional well-being (B = 0.6; 95% CI, 0.03-1.2) scores. Reallocating 30 minutes of light activity to 30 minutes of MVPA was associated with improved FACT-B total (B = 2.4; 95% CI, 0.3-6.0) and physical well-being (B = 0.72; 95% CI, 0.27-1.2) scores. There was no significant substitution of time effects on HADS scores. Conclusions: Substituting sedentary time with MVPA showed the greatest range of effects across QOL indicators. These results can inform intervention development interventions and more comprehensive activity recommendations for breast cancer survivors.

Original languageEnglish (US)
Pages (from-to)1430-1437
Number of pages8
JournalPsycho-Oncology
Volume28
Issue number7
DOIs
StatePublished - Jul 1 2019

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Survivors
Quality of Life
Exercise
Breast Neoplasms
Anxiety
Accelerometry
Depression
Observational Studies
Breast
Light
Neoplasms

Keywords

  • breast cancer survivors
  • cancer
  • oncology
  • physical activity
  • sedentary behavior

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Oncology
  • Psychiatry and Mental health

Cite this

Effects of reallocating sedentary time with physical activity on quality of life indicators in breast cancer survivors. / Welch, Whitney A.; Ehlers, Diane; Gavin, Kara L.; Aguinaga, Susan; Cottrell, Alison; Nielsen, Anne; Solk, Payton; McAuley, Edward; Phillips, Siobhan M.

In: Psycho-Oncology, Vol. 28, No. 7, 01.07.2019, p. 1430-1437.

Research output: Contribution to journalArticle

Welch, Whitney A. ; Ehlers, Diane ; Gavin, Kara L. ; Aguinaga, Susan ; Cottrell, Alison ; Nielsen, Anne ; Solk, Payton ; McAuley, Edward ; Phillips, Siobhan M. / Effects of reallocating sedentary time with physical activity on quality of life indicators in breast cancer survivors. In: Psycho-Oncology. 2019 ; Vol. 28, No. 7. pp. 1430-1437.
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abstract = "Objectives: Physical activity is associated with better quality of life (QOL) among breast cancer survivors. However, it is unknown the extent to which time spent sedentary or replacing this time with active behaviors may affect QOL. Our aim was to determine the effect of substituting time between sedentary and active behaviors on QOL indicators in breast cancer survivors. Methods: An isotemporal substitution approach was used to examine the associations of reallocating time to sedentary and active behaviors measured by accelerometry with Functional Assessment of Cancer Treatment—Breast (FACT-B; total, physical, social, emotional, functional well-being, and breast cancer–specific concerns) and the Hospital Anxiety and Depression Scale (HADS) scores in a pooled analysis of breast cancer survivors (n = 753; Mage = 56.9 ± 9.5 y) from two observational studies. Results: Reallocating 30 minutes of sedentary time to 30 minutes of moderate-to-vigorous intensity physical activity (MVPA) was associated with improved FACT-B total (B = 3.0; 95{\%} CI, 0.6-4.5), physical well-being (B = 0.8; 95{\%} CI, 0.33-1.2), and functional well-being (B = 0.6; 95{\%} CI, 0.03-1.2) scores. Reallocating 30 minutes of light activity to 30 minutes of MVPA was associated with improved FACT-B total (B = 2.4; 95{\%} CI, 0.3-6.0) and physical well-being (B = 0.72; 95{\%} CI, 0.27-1.2) scores. There was no significant substitution of time effects on HADS scores. Conclusions: Substituting sedentary time with MVPA showed the greatest range of effects across QOL indicators. These results can inform intervention development interventions and more comprehensive activity recommendations for breast cancer survivors.",
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AU - Welch, Whitney A.

AU - Ehlers, Diane

AU - Gavin, Kara L.

AU - Aguinaga, Susan

AU - Cottrell, Alison

AU - Nielsen, Anne

AU - Solk, Payton

AU - McAuley, Edward

AU - Phillips, Siobhan M.

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N2 - Objectives: Physical activity is associated with better quality of life (QOL) among breast cancer survivors. However, it is unknown the extent to which time spent sedentary or replacing this time with active behaviors may affect QOL. Our aim was to determine the effect of substituting time between sedentary and active behaviors on QOL indicators in breast cancer survivors. Methods: An isotemporal substitution approach was used to examine the associations of reallocating time to sedentary and active behaviors measured by accelerometry with Functional Assessment of Cancer Treatment—Breast (FACT-B; total, physical, social, emotional, functional well-being, and breast cancer–specific concerns) and the Hospital Anxiety and Depression Scale (HADS) scores in a pooled analysis of breast cancer survivors (n = 753; Mage = 56.9 ± 9.5 y) from two observational studies. Results: Reallocating 30 minutes of sedentary time to 30 minutes of moderate-to-vigorous intensity physical activity (MVPA) was associated with improved FACT-B total (B = 3.0; 95% CI, 0.6-4.5), physical well-being (B = 0.8; 95% CI, 0.33-1.2), and functional well-being (B = 0.6; 95% CI, 0.03-1.2) scores. Reallocating 30 minutes of light activity to 30 minutes of MVPA was associated with improved FACT-B total (B = 2.4; 95% CI, 0.3-6.0) and physical well-being (B = 0.72; 95% CI, 0.27-1.2) scores. There was no significant substitution of time effects on HADS scores. Conclusions: Substituting sedentary time with MVPA showed the greatest range of effects across QOL indicators. These results can inform intervention development interventions and more comprehensive activity recommendations for breast cancer survivors.

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