Effects of estrogen deficiency on brain function. Implications for the treatment of postmenopausal women.

S. J. Birge, B. S. McEwen, P. M. Wise

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    A growing body of evidence suggests that postmenopausal estrogen deficiency accelerates brain aging and increases the risk of various neurodegenerative processes, including Alzheimer's disease. Recent preclinical and clinical studies have indicated that estrogen has positive effects on brain homeostasis by preserving neural plasticity and the neurotransmitter pathways involved in learning, memory, and balance. In this article, Dr Birge and his coauthors address the effects of estrogen on brain function and discuss their implications for the use of selective estrogen receptor modulators, particularly tamoxifen and raloxifene, in postmenopausal women.

    Original languageEnglish (US)
    Pages (from-to)11-16
    Number of pages6
    JournalPostgraduate medicine
    VolumeSpec No
    StatePublished - Mar 2001

    ASJC Scopus subject areas

    • Medicine(all)

    Fingerprint

    Dive into the research topics of 'Effects of estrogen deficiency on brain function. Implications for the treatment of postmenopausal women.'. Together they form a unique fingerprint.

    Cite this