Effects of emotional context on impulse control

Matthew R.G. Brown, R. Marc Lebel, Florin Dolcos, Alan H. Wilman, Peter H. Silverstone, Hannah Pazderka, Esther Fujiwara, T. Cameron Wild, Alan M. Carroll, Oleksandr Hodlevskyy, Lenka Zedkova, Lonnie Zwaigenbaum, Angus H. Thompson, Andrew J. Greenshaw, Serdar M. Dursun

Research output: Contribution to journalArticle

Abstract

High risk behaviors such as narcotic use or physical fighting can be caused by impulsive decision making in emotionally-charged situations. Improved neuroscientific understanding of how emotional context interacts with the control of impulsive behaviors may lead to advances in public policy and/or treatment approaches for high risk groups, including some high-risk adolescents or adults with poor impulse control. Inferior frontal gyrus (IFG) is an important contributor to response inhibition (behavioral impulse control). IFG also has a role in processing emotional stimuli and regulating emotional responses. The mechanism(s) whereby response inhibition processes interact with emotion processing in IFG are poorly understood. We used 4.7. T fMRI in 20 healthy young adults performing a rapid event-related emotional Go/NoGo task. This task combined the Go/NoGo task, which is a classic means of recruiting response inhibition processes, with emotionally neutral and aversive distractor images. In IFG, both response inhibition in an emotionally neutral context (neutral NoGo trials) and aversive emotional picture processing (aversive Go trials) evoked activation greater than the simple response baseline (neutral Go trials). These results are consistent with the literature. Activation for response inhibition in aversive contexts (aversive NoGo-neutral Go trials) was approximately the sum of response inhibition activation (neutral NoGo-neutral Go) and aversive emotional distractor activation (aversive Go-neutral Go). We conclude that response inhibition and aversive emotional stimulus processing activities combine additively (linearly) in IFG, rather than interfering with each other (sub-linearly) or mutually-enhancing each other (super-linearly). We also found previously undocumented interaction effects between response inhibition (NoGo vs. Go) and emotional context (aversive vs. neutral distractor pictures) in bilateral posterior middle temporal gyrus and angular gyrus, right frontal eye field, and other brain regions. These results may reflect the interaction of attention processes driven by emotional stimuli with conflict resolution processes related to Go/NoGo performance.

Original languageEnglish (US)
Pages (from-to)434-446
Number of pages13
JournalNeuroImage
Volume63
Issue number1
DOIs
StatePublished - Oct 15 2012

Fingerprint

Prefrontal Cortex
Parietal Lobe
Inhibition (Psychology)
Impulsive Behavior
Narcotics
Negotiating
Frontal Lobe
Temporal Lobe
Public Policy
Risk-Taking
Young Adult
Decision Making
Emotions
Magnetic Resonance Imaging
Brain
Therapeutics

Keywords

  • Distractor
  • Emotion
  • Functional magnetic resonance imaging
  • IAPS
  • Impulse control
  • NoGo
  • Response inhibition
  • Valence

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

Brown, M. R. G., Lebel, R. M., Dolcos, F., Wilman, A. H., Silverstone, P. H., Pazderka, H., ... Dursun, S. M. (2012). Effects of emotional context on impulse control. NeuroImage, 63(1), 434-446. https://doi.org/10.1016/j.neuroimage.2012.06.056

Effects of emotional context on impulse control. / Brown, Matthew R.G.; Lebel, R. Marc; Dolcos, Florin; Wilman, Alan H.; Silverstone, Peter H.; Pazderka, Hannah; Fujiwara, Esther; Wild, T. Cameron; Carroll, Alan M.; Hodlevskyy, Oleksandr; Zedkova, Lenka; Zwaigenbaum, Lonnie; Thompson, Angus H.; Greenshaw, Andrew J.; Dursun, Serdar M.

In: NeuroImage, Vol. 63, No. 1, 15.10.2012, p. 434-446.

Research output: Contribution to journalArticle

Brown, MRG, Lebel, RM, Dolcos, F, Wilman, AH, Silverstone, PH, Pazderka, H, Fujiwara, E, Wild, TC, Carroll, AM, Hodlevskyy, O, Zedkova, L, Zwaigenbaum, L, Thompson, AH, Greenshaw, AJ & Dursun, SM 2012, 'Effects of emotional context on impulse control', NeuroImage, vol. 63, no. 1, pp. 434-446. https://doi.org/10.1016/j.neuroimage.2012.06.056
Brown MRG, Lebel RM, Dolcos F, Wilman AH, Silverstone PH, Pazderka H et al. Effects of emotional context on impulse control. NeuroImage. 2012 Oct 15;63(1):434-446. https://doi.org/10.1016/j.neuroimage.2012.06.056
Brown, Matthew R.G. ; Lebel, R. Marc ; Dolcos, Florin ; Wilman, Alan H. ; Silverstone, Peter H. ; Pazderka, Hannah ; Fujiwara, Esther ; Wild, T. Cameron ; Carroll, Alan M. ; Hodlevskyy, Oleksandr ; Zedkova, Lenka ; Zwaigenbaum, Lonnie ; Thompson, Angus H. ; Greenshaw, Andrew J. ; Dursun, Serdar M. / Effects of emotional context on impulse control. In: NeuroImage. 2012 ; Vol. 63, No. 1. pp. 434-446.
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