Effect on BOLD sensitivity due to susceptibility-induced echo time shift in spiral-in based functional MRI

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Susceptibility artifacts induced by the magnetic field inhomogeneity exist near the air/tissue interfaces at the ventral brain in functional magnetic resonance imaging (fMRI). These susceptibility artifacts will cause geometric distortions and signal loss in reconstructed images. Additionally, the in-plane susceptibility gradients will cause a shift in effective echo time, and therefore influence the blood-oxygen-level dependent (BOLD) sensitivity since it is proportional to effective echo time. In this work, we examine the effective echo time shift and the change of the BOLD sensitivity based on susceptibility gradients. The analysis results show that there are regions, such as the orbitofrontal cortex, that suffer from significant loss of BOLD sensitivity using spiral-in trajectory in BOLD fMRI.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages4449-4452
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

Fingerprint Dive into the research topics of 'Effect on BOLD sensitivity due to susceptibility-induced echo time shift in spiral-in based functional MRI'. Together they form a unique fingerprint.

  • Cite this

    Zhuo, Y., & Sutton, B. P. (2009). Effect on BOLD sensitivity due to susceptibility-induced echo time shift in spiral-in based functional MRI. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 4449-4452). [5333815] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5333815