Effect of tinnitus on distortion product otoacoustic emissions varies with hearing loss

Research output: Contribution to journalArticle

Abstract

Purpose: The aim of this study was to measure the effect of tinnitus, while accounting for the effect of hearing loss and aging, on distortion product otoacoustic emissions (DPOAEs). Method: DPOAEs were measured twice in both ears in 5 groups of participants: young adults with normal hearing, middle-age adults with normal hearing, adults with high-frequency sensorineural hearing loss, age-matched adults with similar hearing loss and tinnitus, and adults with normal hearing and chronic tinnitus. Results: Multivariate analysis revealed a main effect of hearing loss and age, but no effect of tinnitus, across all 5 groups. Separate tests revealed significant effects of age and tinnitus in the normal-hearing groups and hearing loss in adults with or without tinnitus, but no effect of tinnitus in those with hearing loss. Conclusion: DPOAE levels in the group of adults with hearing loss and tinnitus were diminished, but those in the group with normal hearing and tinnitus were enhanced, relative to DPOAE levels in the controls. Outer hair cell function, as indexed by DPOAEs, exhibits a complex association with tinnitus, and this has implications in the use of DPOAEs as a tool both for testing for tinnitus presence and for creating a model of neural mechanisms underlying tinnitus.

Original languageEnglish (US)
Pages (from-to)125-134
Number of pages10
JournalAmerican journal of audiology
Volume22
Issue number1
DOIs
StatePublished - Jun 1 2013

Keywords

  • Age
  • DP gram
  • Distortion product otoacoustic emissions
  • Hearing loss
  • Outer hair cell
  • Tinnitus

ASJC Scopus subject areas

  • Speech and Hearing

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