Abstract
Concanavalin A delays aggregation of slime mold amoebae, apparently by interfering with the cells' response to the chemotactic agent, cyclic AMP. Concanavalin A also induces the premature appearance in non-aggregating cells of a membrane-bound cyclic AMP phosphodiesterase normally found only at the time of aggregation. The appearance of this enzyme is not due to activation of an inactive form of the enzyme.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1159-1166 |
| Number of pages | 8 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 53 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 21 1973 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
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