TY - JOUR
T1 - Effect of concanavalin A on cellular slime mold development
T2 - Premature appearance of membrane-bound cyclic AMP phosphodiesterase
AU - Gillette, Martha Ulbrick
AU - Filosa, M. F.
N1 - by the National fellowship to
PY - 1973/8/21
Y1 - 1973/8/21
N2 - Concanavalin A delays aggregation of slime mold amoebae, apparently by interfering with the cells' response to the chemotactic agent, cyclic AMP. Concanavalin A also induces the premature appearance in non-aggregating cells of a membrane-bound cyclic AMP phosphodiesterase normally found only at the time of aggregation. The appearance of this enzyme is not due to activation of an inactive form of the enzyme.
AB - Concanavalin A delays aggregation of slime mold amoebae, apparently by interfering with the cells' response to the chemotactic agent, cyclic AMP. Concanavalin A also induces the premature appearance in non-aggregating cells of a membrane-bound cyclic AMP phosphodiesterase normally found only at the time of aggregation. The appearance of this enzyme is not due to activation of an inactive form of the enzyme.
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U2 - 10.1016/0006-291X(73)90586-X
DO - 10.1016/0006-291X(73)90586-X
M3 - Article
C2 - 4356053
AN - SCOPUS:0015799807
SN - 0006-291X
VL - 53
SP - 1159
EP - 1166
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 4
ER -