Concanavalin A delays aggregation of slime mold amoebae, apparently by interfering with the cells' response to the chemotactic agent, cyclic AMP. Concanavalin A also induces the premature appearance in non-aggregating cells of a membrane-bound cyclic AMP phosphodiesterase normally found only at the time of aggregation. The appearance of this enzyme is not due to activation of an inactive form of the enzyme.

Original languageEnglish (US)
Pages (from-to)1159-1166
Number of pages8
JournalBiochemical and Biophysical Research Communications
Issue number4
StatePublished - Aug 21 1973

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Effect of concanavalin A on cellular slime mold development: Premature appearance of membrane-bound cyclic AMP phosphodiesterase'. Together they form a unique fingerprint.

  • Cite this