Concanavalin A delays aggregation of slime mold amoebae, apparently by interfering with the cells' response to the chemotactic agent, cyclic AMP. Concanavalin A also induces the premature appearance in non-aggregating cells of a membrane-bound cyclic AMP phosphodiesterase normally found only at the time of aggregation. The appearance of this enzyme is not due to activation of an inactive form of the enzyme.
|Original language||English (US)|
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Aug 21 1973|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology