Effect of an injectable trace mineral supplement containing selenium, copper, zinc, and manganese on immunity, health, and growth of dairy calves

A. G.V. Teixeira, F. S. Lima, M. L.S. Bicalho, A. Kussler, S. F. Lima, M. J. Felippe, R. C. Bicalho

Research output: Contribution to journalArticle

Abstract

The objective of this study was to evaluate the effect of 2 subcutaneous injections of a multimineral preparation, each containing 60. mg of zinc, 10. mg of manganese, 5. mg of selenium, and 15. mg of copper at 3 and 30. d after birth on immunity, health, and growth of dairy calves during the preweaning period. The study was conducted in upstate New York in 2 commercial dairy farms. A total of 790 Holstein heifer calves were randomly allocated at birth into 1 of 2 treatments: trace mineral supplement (TMS) treated or control. Blood samples were collected at 3, 14, and 35. d after birth to evaluate glutathione peroxidase (GPx) activity, superoxide dismutase (SOD) activity, haptoglobin, and neutrophil and monocyte function. Incidence of diseases and average daily gain was evaluated in the first 50. d of life. At 14. d of life, TMS-treated calves had increased neutrophil activity compared with control calves. Moreover, TMS-treated calves had greater GPx activity on d 14 after birth than control calves. The TMS treatment reduced the incidence of diarrhea (TMS = 41.7% vs. control = 49.7%) and combined incidence of pneumonia or otitis or both (TMS = 41.7% vs. control = 49.1%). Additionally, GPx was greater for calves diagnosed with otitis at d 35 after birth. However, calves diagnosed with pneumonia had decreased GPx activity at d 35 after birth. Serum SOD and haptoglobin concentrations were not affected by treatment or disease. Moreover, no effects were observed on average daily gain and survivability between TMS-treated and control calves during the preweaning period. Supplementation with trace minerals at 3 and 30. d of life increased neutrophil function and GPx activity and reduced the incidence of health disorders.

Original languageEnglish (US)
Pages (from-to)4216-4226
Number of pages11
JournalJournal of Dairy Science
Volume97
Issue number7
DOIs
StatePublished - Jul 2014

Keywords

  • Dairy calf
  • Diarrhea
  • Neutrophil function
  • Trace mineral

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Genetics

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    Teixeira, A. G. V., Lima, F. S., Bicalho, M. L. S., Kussler, A., Lima, S. F., Felippe, M. J., & Bicalho, R. C. (2014). Effect of an injectable trace mineral supplement containing selenium, copper, zinc, and manganese on immunity, health, and growth of dairy calves. Journal of Dairy Science, 97(7), 4216-4226. https://doi.org/10.3168/jds.2013-7625