TY - JOUR
T1 - Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications
AU - Dsouza, Roshan
AU - Won, Jungeun
AU - Monroy, Guillermo L.
AU - Spillman, Darold R.
AU - Boppart, Stephen A.
N1 - Publisher Copyright:
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE).
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT contains all associated optical hardware, including light source, spectrometer, hand-held probe, and a laptop. Additionally, this system utilizes unique real-time mosaicking of surface video images that are synchronized with rapid A-scan acquisition to eliminate the need for lateral scanning hardware, and enable the construction of cross-sectional B-mode images over extended lateral distances. The entire briefcase system weighs 9 kg and costs USD8000 using off-the-shelf components. System performance was validated by acquiring images of in vivo human skin on the fingertip, palm, and nail fold. The efficiency, portability, and low-cost enable accessibility and utility in primary care centers and low-resource settings.
AB - Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT contains all associated optical hardware, including light source, spectrometer, hand-held probe, and a laptop. Additionally, this system utilizes unique real-time mosaicking of surface video images that are synchronized with rapid A-scan acquisition to eliminate the need for lateral scanning hardware, and enable the construction of cross-sectional B-mode images over extended lateral distances. The entire briefcase system weighs 9 kg and costs USD8000 using off-the-shelf components. System performance was validated by acquiring images of in vivo human skin on the fingertip, palm, and nail fold. The efficiency, portability, and low-cost enable accessibility and utility in primary care centers and low-resource settings.
KW - diagnostics
KW - handheld
KW - optical coherence tomography
KW - point-of-care
KW - system development; spectrometers.
UR - http://www.scopus.com/inward/record.url?scp=85054029165&partnerID=8YFLogxK
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U2 - 10.1117/1.JBO.23.9.096003
DO - 10.1117/1.JBO.23.9.096003
M3 - Article
C2 - 30251484
AN - SCOPUS:85054029165
SN - 1083-3668
VL - 23
JO - Journal of biomedical optics
JF - Journal of biomedical optics
IS - 9
M1 - 096003
ER -