TY - JOUR
T1 - Early human dispersals within the Americas
AU - Moreno-Mayar, J. Víctor
AU - Vinner, Lasse
AU - De Barros Damgaard, Peter
AU - De La Fuente, Constanza
AU - Chan, Jeffrey
AU - Spence, Jeffrey P.
AU - Allentoft, Morten E.
AU - Vimala, Tharsika
AU - Racimo, Fernando
AU - Pinotti, Thomaz
AU - Rasmussen, Simon
AU - Margaryan, Ashot
AU - Orbegozo, Miren Iraeta
AU - Mylopotamitaki, Dorothea
AU - Wooller, Matthew
AU - Bataille, Clement
AU - Becerra-Valdivia, Lorena
AU - Chivall, David
AU - Comeskey, Daniel
AU - Devièse, Thibaut
AU - Grayson, Donald K.
AU - George, Len
AU - Harry, Harold
AU - Alexandersen, Verner
AU - Primeau, Charlotte
AU - Erlandson, Jon
AU - Rodrigues-Carvalho, Claudia
AU - Reis, Silvia
AU - Bastos, Murilo Q.R.
AU - Cybulski, Jerome
AU - Vullo, Carlos
AU - Morello, Flavia
AU - Vilar, Miguel
AU - Wells, Spencer
AU - Gregersen, Kristian
AU - Hansen, Kasper Lykke
AU - Lynnerup, Niels
AU - Lahr, Marta Mirazón
AU - Kjær, Kurt
AU - Strauss, André
AU - Alfonso-Durruty, Marta
AU - Salas, Antonio
AU - Schroeder, Hannes
AU - Higham, Thomas
AU - Malhi, Ripan S.
AU - Rasic, Jeffrey T.
AU - Souza, Luiz
AU - Santos, Fabricio R.
AU - Malaspinas, Anna Sapfo
AU - Sikora, Martin
AU - Nielsen, Rasmus
AU - Song, Yun S.
AU - Meltzer, David J.
AU - Willerslev, Eske
N1 - For permission and cooperation in providing human remains for this study, we thank the Native Village of Deering, Alaska; the Fallon Paiute-Shoshone Tribe; the Consejo de Monumentos Nacionales, Chile; and the Canadian Museum of History and the Stswecem’c Xgat’tem, Metlakatla, and Lax Kw’alaams First Nations. See (74, 75) for related analyses of ancient DNA samples from the Americas. We thank J. Ramos-Madrigal, L. Orlando, G. Renaud, F. Vieira, L. Benson, A. Bergström, T. Ferraz, and J. E. Santos-Júnior for discussions; M. Drummond, F. Zimmermann, and T. Tisler for image processing; B. Chestnut, B. Baldwin, and D. Cossette for help and support; and the Danish National High-throughput Sequencing Centre for assistance with data generation. St. John’s College, Cambridge University, provided E.W. and D.J.M. a congenial venue for scientific discussions. Funding: GeoGenetics members were supported by the Lundbeck Foundation, the Danish National Research Foundation (DNRF94), and KU2016. Study of the Lagoa Santa human remains was partly funded by the Augustinus Foundation. J.Ch. is supported in part by an NSF graduate research fellowship. J.Ch., J.P.S., and Y.S.S. are supported in part by the National Institutes of Health grant R01-GM094402, a Microsoft Azure research award, and a Packard Fellowship for Science and Engineering. A.St. was funded by FAPESP (2017/16451-2). Study of Patagonian samples by M.A.-D. was sponsored by the National Geographic Society, Genographic Program, grant 14-01. H.S. was supported by HERA and the European Union’s Horizon2020 Research and Innovation Programme (grant 649307). J.T.R. was supported by
PY - 2018/12/7
Y1 - 2018/12/7
N2 - Studies of the peopling of the Americas have focused on the timing and number of initial migrations. Less attention has been paid to the subsequent spread of people within the Americas.We sequenced 15 ancient human genomes spanning from Alaska to Patagonia; six are =10,000 years old (up to ~18× coverage). All are most closely related to Native Americans, including those from an Ancient Beringian individual and two morphologically distinct “Paleoamericans.” We found evidence of rapid dispersal and early diversification that included previously unknown groups as people moved south. This resulted in multiple independent, geographically uneven migrations, including one that provides clues of a Late Pleistocene Australasian genetic signal, as well as a later Mesoamerican-related expansion. These led to complex and dynamic population histories from North to South America.
AB - Studies of the peopling of the Americas have focused on the timing and number of initial migrations. Less attention has been paid to the subsequent spread of people within the Americas.We sequenced 15 ancient human genomes spanning from Alaska to Patagonia; six are =10,000 years old (up to ~18× coverage). All are most closely related to Native Americans, including those from an Ancient Beringian individual and two morphologically distinct “Paleoamericans.” We found evidence of rapid dispersal and early diversification that included previously unknown groups as people moved south. This resulted in multiple independent, geographically uneven migrations, including one that provides clues of a Late Pleistocene Australasian genetic signal, as well as a later Mesoamerican-related expansion. These led to complex and dynamic population histories from North to South America.
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U2 - 10.1126/science.aav2621
DO - 10.1126/science.aav2621
M3 - Article
C2 - 30409807
AN - SCOPUS:85058604407
SN - 0036-8075
VL - 362
JO - Science
JF - Science
IS - 6419
M1 - eaav2621
ER -