Abstract

A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.

Original languageEnglish (US)
Title of host publicationAsia Communications and Photonics Conference and Exhibition, ACP 2009
PublisherOptical Society of America
ISBN (Print)9781557528773
StatePublished - Jan 1 2009
EventAsia Communications and Photonics Conference and Exhibition, ACP 2009 - Shanghai, China
Duration: Nov 2 2009Nov 6 2009

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Other

OtherAsia Communications and Photonics Conference and Exhibition, ACP 2009
CountryChina
CityShanghai
Period11/2/0911/6/09

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Liang, X., & Boppart, S. A. (2009). Dynamic optical coherence elastography and applications. In Asia Communications and Photonics Conference and Exhibition, ACP 2009 (Optics InfoBase Conference Papers). Optical Society of America.