Abstract

A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.

Original languageEnglish (US)
Title of host publication2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
StatePublished - Dec 1 2009
Event2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 - Shanghai, China
Duration: Nov 2 2009Nov 6 2009

Publication series

Name2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009

Other

Other2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
CountryChina
CityShanghai
Period11/2/0911/6/09

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

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  • Cite this

    Liang, X., & Boppart, S. A. (2009). Dynamic optical coherence elastography and applications. In 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 [5377315] (2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009).