Dynamic optical coherence elastography and applications

Xing Liang; Stephen A. Boppart

Dynamic optical coherence elastography and applications

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.

Original language	English (US)
Title of host publication	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
State	Published - Dec 1 2009
Event	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 - Shanghai, China Duration: Nov 2 2009 → Nov 6 2009

Publication series

Name	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009

Other

Other	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
Country	China
City	Shanghai
Period	11/2/09 → 11/6/09

ASJC Scopus subject areas

Electrical and Electronic Engineering
Electronic, Optical and Magnetic Materials

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Cite this

@inproceedings{ab9312204b554a0fa8ee60a6439ae8ef,

title = "Dynamic optical coherence elastography and applications",

abstract = "A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.",

author = "Xing Liang and Boppart, {Stephen A.}",

year = "2009",

month = dec,

day = "1",

language = "English (US)",

isbn = "9781557528773",

series = "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",

booktitle = "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009",

note = "2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 ; Conference date: 02-11-2009 Through 06-11-2009",

}

TY - GEN

T1 - Dynamic optical coherence elastography and applications

AU - Liang, Xing

AU - Boppart, Stephen A.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.

AB - A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.

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UR - http://www.scopus.com/inward/citedby.url?scp=77949356609&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:77949356609

SN - 9781557528773

T3 - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009

BT - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009

T2 - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009

Y2 - 2 November 2009 through 6 November 2009

ER -