TY - GEN
T1 - Dynamic optical coherence elastography and applications
AU - Liang, Xing
AU - Boppart, Stephen A.
PY - 2009/12/1
Y1 - 2009/12/1
N2 - A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.
AB - A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured on human skin from different sites, orientations, and frequencies.
UR - http://www.scopus.com/inward/record.url?scp=77949356609&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77949356609&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:77949356609
SN - 9781557528773
T3 - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
BT - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
T2 - 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
Y2 - 2 November 2009 through 6 November 2009
ER -