Abstract

Dynamic optical coherence elastography, an emerging optical technique to measure material mechanical properties using the non-invasive imaging modality of optical coherence tomography is introduced. Dynamic mechanical excitations were applied to the samples while a spectral domain optical coherence tomography system was used for detection. Based on a simple mechanical model, material mechanical properties such as Young's moduli can be extracted from detected phaseresolved signals. Biological tissues and their biomechanical properties are currently the main objects for this technique due to its micron-scale resolution and relatively deep penetration. Quantitative results were achieved by this technique on tissue phantoms and rat tumor tissues. Different excitation approaches and applications for dynamic optical coherence elastography are also discussed.

Original languageEnglish (US)
Title of host publicationOptical Sensors and Biophotonics
DOIs
StatePublished - Dec 1 2009
EventOptical Sensors and Biophotonics - Shanghai, China
Duration: Nov 2 2009Nov 6 2009

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7634
ISSN (Print)0277-786X

Other

OtherOptical Sensors and Biophotonics
CountryChina
CityShanghai
Period11/2/0911/6/09

Keywords

  • Elastography
  • Optical coherence tomography
  • Tumor biomechanical properties
  • Young's modulus

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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  • Cite this

    Liang, X., & Boppart, S. A. (2009). Dynamic optical coherence elastography and applications. In Optical Sensors and Biophotonics [763403] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 7634). https://doi.org/10.1117/12.852477