Abstract

With the development of optical coherence tomography, the application optical coherence elastography (OCE) has gained more and more attention in biomechanics for its unique features including micron-scale resolution, real-time processing, and non-invasive imaging. In this review, one group of OCE techniques, namely dynamic OCE, are introduced and discussed including external dynamic OCE mapping and imaging of ex vivo breast tumor, external dynamic OCE measurement of in vivo human skin, and internal dynamic OCE including acoustomotive OCE and magnetomotive OCE. These techniques overcame some of the major drawbacks of traditional static OCE, and broadened the OCE application fields. Driven by scientific needs to engineer new quantitative methods that utilize the high micron-scale resolution achievable with optics, results of biomechanical properties were obtained from biological tissues. The results suggest potential diagnostic and therapeutic clinical applications. Results from these studies also help our understanding of the relationship between biomechanical variations and functional tissue changes in biological systems.

Original languageEnglish (US)
Pages (from-to)221-233
Number of pages13
JournalJournal of Innovative Optical Health Sciences
Volume3
Issue number4
DOIs
StatePublished - Oct 1 2010

Fingerprint

Elasticity Imaging Techniques
Tissue
Imaging techniques
biodynamics
Biomechanics
Optical tomography
Optical Coherence Tomography
Optical resolving power
Biological systems
Biomechanical Phenomena
breast
Tumors
Optics
engineers
Skin
tumors
tomography
Breast Neoplasms

Keywords

  • biomechanics
  • optical coherence elastography
  • Optical coherence tomography
  • phase measurements
  • scattering
  • tissue characterization

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Medicine (miscellaneous)

Cite this

Dynamic optical coherence elastography : A review. / Liang, Xing; Crecea, Vasilica; Boppart, Stephen A.

In: Journal of Innovative Optical Health Sciences, Vol. 3, No. 4, 01.10.2010, p. 221-233.

Research output: Contribution to journalReview article

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