TY - PAT
T1 - Dye-conjugated dendrimers
AU - Kim, Younghoon
AU - Schroeder III, Charles M
AU - Tanyeri, Melikhan
AU - Katzenellenbogen, John A
AU - Kim, Sung Hoon
N1 - GOVERNMENT SUPPORT This invention was made with government support under Grant Nos. R00HG004183 and R01 DK015556, both awarded by the National Institutes of Health. The United States Government has certain rights in the invention.
PY - 2016/9/20
Y1 - 2016/9/20
N2 - The invention provides dendrimers, conjugates thereof, and methods of using dendrimer conjugates. In one embodiment, the invention provides novel polymeric dendrimers as a new class of fluorescent labels. The labels can include multiple fluorescent dye molecules conjugated to a single polymeric backbone or core, such as a dendrimer. The dendrimers can have regular or irregular branched polymeric network structures that allow for the chemical attachment of multiple dye molecules, multiple color dyes, and/or multiple functional groups, in a combinatorial fashion. The fluorescent dendritic nanoprobes (FDNs) thus provide a new class of fluorescent reporters for fluorescence microscopy and imaging.
AB - The invention provides dendrimers, conjugates thereof, and methods of using dendrimer conjugates. In one embodiment, the invention provides novel polymeric dendrimers as a new class of fluorescent labels. The labels can include multiple fluorescent dye molecules conjugated to a single polymeric backbone or core, such as a dendrimer. The dendrimers can have regular or irregular branched polymeric network structures that allow for the chemical attachment of multiple dye molecules, multiple color dyes, and/or multiple functional groups, in a combinatorial fashion. The fluorescent dendritic nanoprobes (FDNs) thus provide a new class of fluorescent reporters for fluorescence microscopy and imaging.
M3 - Patent
M1 - 9448173
Y2 - 2012/03/08
ER -