TY - JOUR
T1 - Drug therapies for uterine fibroids
T2 - A new approach to an old problem
AU - Nowak, Romana A.
PY - 2004/10
Y1 - 2004/10
N2 - Uterine fibroids are a significant problem in women's health and account for almost 40% of hysterectomies performed annually in the U.S. Until recently, medical treatments focused on drugs that block estrogen production and action. These have had limited success. Now, several novel compounds including selective progesterone receptor modulators and anti-fibrotic drugs such as pirfenidone, halofuginone, and interferons (INFs) are being investigated and show promise for the treatment of these tumors.
AB - Uterine fibroids are a significant problem in women's health and account for almost 40% of hysterectomies performed annually in the U.S. Until recently, medical treatments focused on drugs that block estrogen production and action. These have had limited success. Now, several novel compounds including selective progesterone receptor modulators and anti-fibrotic drugs such as pirfenidone, halofuginone, and interferons (INFs) are being investigated and show promise for the treatment of these tumors.
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U2 - 10.1016/j.ddstr.2004.08.021
DO - 10.1016/j.ddstr.2004.08.021
M3 - Review article
AN - SCOPUS:13344283334
SN - 1740-6773
VL - 1
SP - 237
EP - 242
JO - Drug Discovery Today: Therapeutic Strategies
JF - Drug Discovery Today: Therapeutic Strategies
IS - 2
ER -