TY - JOUR
T1 - Double-mode relaxation of highly deformed anisotropic vesicles
AU - Kumar, Dinesh
AU - Richter, Channing M.
AU - Schroeder, Charles M.
N1 - Funding Information:
We thank Noah Hopkins for assistance in analyzing experimental data. This work was supported by National Science Foundation by Award No. NSF CBET 1704668.
Publisher Copyright:
© 2020 American Physical Society.
PY - 2020/7
Y1 - 2020/7
N2 - Lipid vesicles are known to undergo complex conformational transitions, but it remains challenging to systematically characterize nonequilibrium membrane dynamics in flow. Here, we report the direct observation of anisotropic vesicle relaxation from highly deformed shapes using a Stokes trap. Vesicle shape relaxation is described by two distinct characteristic timescales governed by the bending modulus and membrane tension. Interestingly, the fast double-mode timescale is found to depend on vesicle deflation or reduced volume. Experimental results are well described by a viscoelastic model of a deformed membrane. Overall, these results show that vesicle relaxation is governed by an interplay between membrane elastic moduli, surface tension, and vesicle deflation.
AB - Lipid vesicles are known to undergo complex conformational transitions, but it remains challenging to systematically characterize nonequilibrium membrane dynamics in flow. Here, we report the direct observation of anisotropic vesicle relaxation from highly deformed shapes using a Stokes trap. Vesicle shape relaxation is described by two distinct characteristic timescales governed by the bending modulus and membrane tension. Interestingly, the fast double-mode timescale is found to depend on vesicle deflation or reduced volume. Experimental results are well described by a viscoelastic model of a deformed membrane. Overall, these results show that vesicle relaxation is governed by an interplay between membrane elastic moduli, surface tension, and vesicle deflation.
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U2 - 10.1103/PhysRevE.102.010605
DO - 10.1103/PhysRevE.102.010605
M3 - Article
C2 - 32794982
AN - SCOPUS:85089476588
VL - 102
JO - Physical Review E
JF - Physical Review E
SN - 2470-0045
IS - 1
M1 - 010605
ER -